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Chloraseptic Total Sore Throat+Cough Lozenges Side Effects

Generic Name: benzocaine / dextromethorphan / menthol

Note: This document contains side effect information about benzocaine / dextromethorphan / menthol. Some of the dosage forms listed on this page may not apply to the brand name Chloraseptic Total Sore Throat+Cough Lozenges.

Applies to benzocaine/dextromethorphan/menthol: mucous membrane lozenge


Frequency not reported: Angioedema

Rare (less than 0.1%): Fixed-drug eruptions
Frequency not reported: Angioedema[Ref]


Frequency not reported: Contact dermatitis, urticaria

Frequency not reported: Pruritus, rash, urticaria[Ref]


Frequency not reported: Burning, stinging

Frequency not reported: Application site redness/irritation[Ref]


Frequency not reported: Abdominal pain, diarrhea, gastrointestinal disturbance, nausea, upset stomach, vomiting[Ref]


Frequency not reported: Abuse, excitation, insomnia, mental confusion[Ref]

Nervous system

Frequency not reported: Convulsions, dizziness, drowsiness[Ref]


Postmarketing reports: Methemoglobinemia[Ref]


Frequency not reported: Respiratory depression[Ref]


Frequency not reported: Edema[Ref]


1. "Product Information. Cold & Hot (menthol topical)." Major Pharmaceuticals Inc, Livonia, MI.

2. "Product Information. Cepacol Lozenges (cetylpyridinium topical)." GlaxoSmithKline Inc, Oakville, IA.

3. "Product Information. Lanacane (benzocaine topical)." Combe Inc, White Plains, NY.

4. Stubb S, Reitamo S "Fixed-drug eruption due to dextromethorphan ." Arch Dermatol 126 (1990): 970-1

5. "Product Information. Chloraseptic (benzocaine topical)." Procter and Gamble Pharmaceuticals, Mason, OH.

6. "Product Information. Dermoplast (benzocaine topical)." MedTech Inc, Irvington, NY.

7. Knowles SR, Weber E "Dextromethorphan anaphylaxis." J Allerg Clin Immunol 102 (1998): 316-7

8. Hall RC, Beresford TP, Stickney SK, Nasdahl CS, Coleman JH "Psychiatric reactions produced by respiratory drugs." Psychosomatics 26 (1985): 605-8,616-7

9. Throm MJ, Stevens MD, Hansen C "Benzocaine-induced methemoglobinemia in two patients: interdisciplinary collaboration, management, and near misses." Pharmacotherapy 27 (2007): 1206-14

10. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

11. Helfer J, Kim OM "Psychoactive abuse potential of Robitussin-DM." Am J Psychiatry 147 (1990): 672-3

12. Bostwick JM "Dextromethorphan-induced manic symptoms in a bipolar patient on lithium." Psychosomatics 37 (1996): 571-2

13. "Product Information. Solarcaine Plus Aloe (benzocaine topical)." Schering-Plough Healthcare Products, Memphis, TN.

14. Murray S, Brewerton T "Abuse of over-the-counter dextromethorphan by teenagers." South Med J 86 (1993): 1151-3

15. "Product Information. Outgro Pain Relief (benzocaine topical)." MedTech Inc, Irvington, NY.

16. "Product Information. Vagisil Feminine Cream (benzocaine topical)." Combe Inc, White Plains, NY.

17. "Product Information. Stopain (menthol topical)." DRJ Group Inc, Carlsbad, CA.

18. "Product Information. Hurricaine (benzocaine topical)." Beutlich, Waukegan, IL.

19. "Product Information. BENGAY Pain Relieving (menthol topical)." Pfizer U.S. Pharmaceuticals Group, New York, NY.

20. Wolfe TR, Caravati EM "Massive dextromethorphan ingestion and abuse." Am J Emerg Med 13 (1995): 174-6

21. Polles A, Griffith JL "Dextromethorphan-induced mania." Psychosomatics 37 (1996): 71-4

22. "Product Information. Americaine Hemorrhoidal (benzocaine topical)." Novartis Consumer Health, Parsippany, NJ.

Some side effects of Chloraseptic Total Sore Throat+Cough Lozenges may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

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