Calcium carbonate / magnesium carbonate Side Effects
Renal side effects have included renal failure, formation of renal calcium, and a single case report of a calcium carbonate and calcium phosphate-filled renal cyst.[Ref]
Gastrointestinal side effects have included rebound hyperacidity, constipation (6% to 37%) and gallstones (rarely) with chronic use of calcium carbonate.
Gastrointestinal side effects have included flatulence and diarrhea with frequent use of magnesium salts. Magnesium (Mg) toxicity has been associated with nausea (Mg levels of 4 to 5 mEq/L) and rare cases of paralytic ileus (Mg levels greater than 5 mEq/L).[Ref]
Rebound hyperacidity has been associated with calcium salt antacids. This side effect does not appear to be due to the acid buffering capacity of calcium carbonate, but is a consequence of a specific action of calcium on the parietal cell.
Rare cases of calcium carbonate gallstones have been reported in the pediatric literature.[Ref]
1. "Product Information. MagneBind 300 (calcium carbonate-magnesium carbonate)." Nephro-Tech Inc, Shawnee, KS.
2. "Multum Information Services, Inc. Expert Review Panel"
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Some side effects may not be reported. You may report them to the FDA.