Caffeine / magnesium salicylate Side Effects
Nervous system side effects associated with caffeine consumption have included central nervous system stimulation such as irritability, restlessness, and jitteriness. Tinnitus and subjective hearing loss (or both) may occur with salicylate. Some investigators have reported that modest doses may result in decreased frequency selectivity and may therefore impair hearing performance, particularly in the setting of background noise.[Ref]
Other side effects have included Reye's syndrome with salicylate use in children with an acute viral illness. Reye's syndrome has also been reported even more rarely in adults.[Ref]
In general, consumption of higher doses of caffeine (less than 600 mg/day) has been reported to have lead to caffeinism. Caffeinism is a syndrome characterized by anxiety, restlessness, and sleep disorders (similar to anxiety states). It has also been reported that chronic, heavy caffeine ingestion may be associated with depression. Caffeine may cause anxiety and panic in panic disorder patients and may aggravate premenstrual syndrome (PMS).[Ref]
Renal side effects associated with caffeine consumption have included increased urine flow rate, creatinine clearance, and sodium and calcium excretion.[Ref]
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Some side effects may not be reported. You may report them to the FDA.