Brenzavvy Side Effects

Generic name: bexagliflozin

Medically reviewed by Drugs.com. Last updated on Mar 22, 2025.

Note: This document provides detailed information about Brenzavvy Side Effects associated with bexagliflozin. Some dosage forms listed on this page may not apply specifically to the brand name Brenzavvy.

Applies to bexagliflozin: oral tablet.

Serious side effects of Brenzavvy

Along with its needed effects, bexagliflozin (the active ingredient contained in Brenzavvy) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking bexagliflozin:

More common side effects

• bladder pain
• bloody or cloudy urine
• difficult, burning, or painful urination
• frequent urination
• increased urge to urinate during the night
• increased volume of pale, dilute urine
• itching of the vagina or genitals
• lower back or side pain
• thick, white vaginal discharge with mild or no odor
• trouble in holding or releasing urine
• walking to urinate at night

Less common side effects

• anxiety
• blurred vision
• chills
• cold sweats
• coma
• confusion
• cool, pale skin
• depression
• dizziness, faintness, or lightheadedness when getting up suddenly from lying or sitting position
• dry mouth
• fast heartbeat
• feeling of constant movement of self or surroundings
• foul smelling discharge from the penis
• headache
• increase in heart rate
• increased hunger
• itching in genital or other skin areas
• nausea
• nervousness
• nightmares
• pain in the skin around the penis
• rapid breathing
• rash of the penis
• redness, itching, or swelling of the penis
• scaling
• seizures
• sensation of spinning
• shakiness
• slurred speech
• sunken eyes
• thirst
• unusual tiredness or weakness
• wrinkled skin

Incidence not known

• agitation
• flushed, dry skin
• fruit-like breath odor
• hostility
• irritability
• lethargy
• loss of consciousness
• muscle twitching
• pain, tenderness, redness, or swelling of the area between the anus and genitals
• stomach pain
• stupor
• sweating
• swelling of the face, ankles, or hands
• trouble breathing
• unexplained weight loss
• vomiting

Other side effects of Brenzavvy

Some side effects of bexagliflozin may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common side effects

• blistering, crusting, irritation, itching, or reddening of the skin
• cracked, dry, or scaly skin

For healthcare professionals

Applies to bexagliflozin: oral tablet.

General adverse events

Most common adverse reactions with an incidence of 5% or greater were female genital mycotic infection, urinary tract infection and increased urination.^[Ref]

Dermatologic

• Common (1% to 10%): Rash and dermatitis^[Ref]

Gastrointestinal

• Common (1% to 10%): Thirst^[Ref]

Genitourinary

• Common (1% to 10%): Female genital mycotic infection, male genital mycotic infection, vaginal pruritus^[Ref]

Metabolic

• Common (1% to 10%): Hypoglycemia, volume depletion^[Ref]

Other

• Common (1% to 10%): Amputation, sepsis^[Ref]

Renal

• Common (1% to 10%): Increased urination, urinary tract infection^[Ref]

Further information

Brenzavvy side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer