Brenzavvy Dosage

Testing Prior to Initiation and During Treatment with BRENZAVVY

• Assess renal function prior to initiation of BRENZAVVY and periodically thereafter as clinically indicated. BRENZAVVY is not recommended in patients with an eGFR less than 30 mL/min/1.73 m2

• Assess volume status. In patients with volume depletion, correct this condition before initiating BRENZAVVY.

Recommended Dosage

• The recommended dosage of BRENZAVVY is 20 mg orally taken once daily in the morning, with or without food.
• Do not crush or chew the tablet.
• If a dose is missed, take the missed dose as soon as possible. Do not double the next dose.

Temporary Interruption for Surgery

• Withhold BRENZAVVY for at least 3 days, if possible, prior to major surgery or procedures associated with prolonged fasting. Resume BRENZAVVY when the patient is clinically stable and has resumed oral intake.