BexxarTherapeutic Side Effects
Generic Name: tositumomab
Note: This document contains side effect information about tositumomab. Some of the dosage forms listed on this page may not apply to the brand name BexxarTherapeutic.
Applies to tositumomab: intravenous kit
Common (1% to 10%): Hypothyroidism[Ref]
Common (1% to 10%): Allergic (hypersensitivity) reactions (allergic reaction, facial edema, injection site hypersensitivity, anaphylactic reaction, laryngismus, serum sickness)
Postmarketing reports: Hypersensitivity reactions including fatal anaphylaxis[Ref]
Very common (10% or more): Positive serology for human anti-mouse antibodies (HAMA)[Ref]
Frequency not reported: Infusion reactions[Ref]
Common (1% to 10%): Secondary malignancies (non-melanoma skin, colorectal, head and neck, breast, lung, bladder, melanoma, gastric)
Frequency not reported: Secondary leukemia, myelodysplastic syndrome[Ref]
1. "Product Information. Bexxar I 131 Therapeutic (iodine I 131 tositumomab)." GlaxoSmithKline, Research Triangle Park, NC.
2. "Product Information. BexxarTherapy (tositumomab)." GlaxoSmithKline Inc, Oakville, IA.
Some side effects of BexxarTherapeutic may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.
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