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Betoptic S Side Effects

Generic Name: betaxolol ophthalmic

Note: This page contains information about the side effects of betaxolol ophthalmic. Some of the dosage forms included on this document may not apply to the brand name Betoptic S.

In Summary

Common side effects of Betoptic S include: eye pain. See below for a comprehensive list of adverse effects.

For the Consumer

Applies to betaxolol ophthalmic: ophthalmic solution, ophthalmic suspension

In addition to its needed effects, some unwanted effects may be caused by betaxolol ophthalmic (the active ingredient contained in Betoptic S). In the event that any of these side effects do occur, they may require medical attention.

Major Side Effects

You should check with your doctor immediately if any of these side effects occur when taking betaxolol ophthalmic:

More common:
  • Eye pain
  • Blistering, peeling, or loosening of the skin
  • blue lips, fingernails, or skin
  • blurred vision
  • change in color vision
  • chest pain or discomfort
  • chills
  • cough
  • crusting of eyelashes
  • decreased urine output
  • decreased vision
  • diarrhea
  • different size pupils of the eyes
  • difficulty in breathing, chewing, swallowing, or talking
  • difficulty seeing at night
  • dilated neck veins
  • double vision
  • drainage from eyes
  • drooping eyelids
  • extreme fatigue
  • fast, slow, or irregular heartbeat
  • feeling of having something in the eye
  • hives, itching skin, or rash
  • increased sensitivity of the eyes to sunlight
  • irregular, fast or slow, or shallow breathing
  • irritation or inflammation of the eye
  • itching, dryness of the eyes
  • joint or muscle pain
  • lightheadedness, dizziness, or fainting
  • muscle weakness
  • noisy breathing
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • red skin lesions, often with a purple center
  • red, irritated eyes
  • severe tiredness
  • sore throat
  • sores, ulcers, or white spots in the mouth or on the lips
  • sweating
  • swelling of the eyelids
  • swelling of the face, fingers, feet, or lower legs
  • tearing
  • thickened mucous from the lungs
  • tightness in the chest
  • troubled breathing
  • unusual tiredness or weakness
  • weight gain

Minor Side Effects

Some of the side effects that can occur with betaxolol ophthalmic may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

  • Bad, unusual, or unpleasant (after) taste
  • change in sense of smell
  • change in taste
  • discouragement
  • feeling of constant movement of self or surroundings
  • feeling sad or empty
  • hair loss
  • headache
  • irritability
  • lack of appetite
  • loss of interest or pleasure
  • redness, swelling, or soreness of tongue
  • sensation of spinning
  • tiredness
  • trouble concentrating
  • trouble sleeping
  • unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness

For Healthcare Professionals

Applies to betaxolol ophthalmic: ophthalmic solution, ophthalmic suspension


The most commonly reported side effect was eye discomfort.[Ref]


Very common (10% or more): Eye discomfort (16%)
Common (1% to 10%): Foreign body sensation in eyes
Uncommon (0.1% to 1%): Tearing on instillation of the drops, punctate keratitis, asthenopia, eye discharge, eyelid margin crusting, conjunctival disorder, conjunctival edema, ocular hyperemia
Rare (less than 0.1%): Signs and symptoms of ocular irritation (e.g., burning, stinging, itching, tearing, redness), pain, corneal punctuate staining, decreased corneal sensitivity, dry eyes, blepharitis, keratitis, blurred vision, anisocoria, photophobia, blepharoconjunctivitis, cataract, refraction disorder
Frequency not reported: Choroidal detachment following filtration surgery, corneal erosion, ptosis, diplopia[Ref]


Rare (less than 0.1%): Systemic allergic reactions including angioedema, urticaria, localized and generalized rash, pruritus, anaphylactic reaction[Ref]


Rare (less than 0.1%): Bradycardia, atrioventricular block, cardiac failure, hypotension, Raynaud's phenomenon, cold hands and feet, exacerbation of intermittent claudication
Frequency not reported: Congestive heart failure, chest pain, palpitations, edema, arrhythmia, cardiac arrest[Ref]


Uncommon (0.1% to 1%): Rhinitis
Rare (less than 0.1%): Bronchospasm (predominantly in patients with pre-existing bronchospastic disease), dyspnea, asthma, rhinorrhea
Frequency not reported: Cough, thickened bronchial secretions, respiratory failure, antral lavage[Ref]


Rare (less than 0.1%): Insomnia, sleep disorders, depression, hallucinations, psychoses, confusion, nightmares[Ref]

Nervous system

Rare (less than 0.1%): Dizziness, paresthesia, headache
Frequency not reported: Memory loss, syncope, cerebrovascular accident, cerebral ischemia, increases in signs and symptoms of myasthenia gravis, dysgeusia, vertigo, lethargy[Ref]


Rare (less than 0.1%): Nausea, vomiting, diarrhea
Frequency not reported: Dyspepsia, dry mouth, abdominal pain, glossitis[Ref]


Rare (less than 0.1%): Alopecia, skin rash
Frequency not reported: Psoriasiform rash or exacerbation of psoriasis, hives, toxic epidermal necrolysis, hair loss, periorbital edema[Ref]


Rare (less than 0.1%): Masking of the symptoms of thyrotoxicosis[Ref]


Rare (less than 0.1%): Sexual dysfunction
Frequency not reported: Decreased libido[Ref]


Rare (less than 0.1%): Increase in anti-nuclear antibodies (ANA)[Ref]


Rare (less than 0.1%): Hypoglycemia[Ref]


Frequency not reported: Myalgia[Ref]


Frequency not reported: Asthenia[Ref]


1. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

2. Cerner Multum, Inc. "Australian Product Information." O 0

3. "Product Information. Betoptic (betaxolol ophthalmic)." Alcon Laboratories Inc, Fort Worth, TX.

Not all side effects for Betoptic S may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.