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Beleodaq Side Effects

Generic name: belinostat

Medically reviewed by Last updated on Jun 26, 2023.

Note: This document contains side effect information about belinostat. Some dosage forms listed on this page may not apply to the brand name Beleodaq.

Applies to belinostat: intravenous powder for solution.

Serious side effects of Beleodaq

Along with its needed effects, belinostat (the active ingredient contained in Beleodaq) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur while taking belinostat:

More common

Incidence not known

Other side effects of Beleodaq

Some side effects of belinostat may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Incidence not known

For Healthcare Professionals

Applies to belinostat: intravenous powder for injection.


The most commonly observed adverse reactions included nausea, fatigue, pyrexia, anemia, and vomiting.

The most commonly reported reasons for treatment discontinuation included anemia, febrile neutropenia, fatigue, and multi-organ failure.[Ref]


Very common (10% or more): Anemia (32%), thrombocytopenia (16%)[Ref]


Very common (10% or more): Peripheral edema (20%), prolonged QT (11%), hypotension (10%), phlebitis (10%)[Ref]


Very common (10% or more): Rash (20%), pruritus (16%)[Ref]


Very common (10% or more): Nausea (43%), vomiting (29%), constipation (23%), diarrhea (23%), decreased appetite (15%), abdominal pain (11%)[Ref]


Very common (10% or more): Hypokalemia (12%)[Ref]

Nervous system

Very common (10% or more): Headache (15%), dizziness (10%)[Ref]


Very common (10% or more): Fatigue (37%), pyrexia (35%), chills (16%)[Ref]


Very common (10% or more): Dyspnea (22%), cough (19%)[Ref]


1. Product Information. Beleodaq (belinostat). Spectrum Pharmaceuticals Inc. 2014.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.