Atropine ophthalmic Side Effects

For the Consumer

Applies to atropine ophthalmic: ophthalmic ointment, ophthalmic solution

Side effects include:

Elevated IOP. With prolonged administration, local irritation, hyperemia, edema, exudate, follicular conjunctivitis, dermatitis.

For Healthcare Professionals

Applies to atropine ophthalmic: ophthalmic ointment, ophthalmic solution

General

The most commonly occurring side effects include blurred vision, photophobia, eye pain and stinging, decreased lacrimation. Systemic effects are more common in infants and elderly.^[Ref]

Cardiovascular

Severe reaction to the ointment may include hypotension.^[Ref]

Frequency not reported: Transient bradycardia followed by tachycardia, palpitations, and arrhythmia^[Ref]

Nervous system

Frequency not reported: Ataxia, restlessness, excitement, irritability, hyperactivity, somnolence, confusion, delirium, hallucinations^[Ref]

Ocular

Common (1% to 10%): Eye pain, stinging, blurred vision, photophobia, decreased lacrimation
Frequency not reported: Superficial keratitis (with prolonged use), conjunctivitis, hyperemia, edema^[Ref]

Gastrointestinal

Frequency not reported: Dry mouth, thirst, dysphagia, nausea, vomiting, constipation^[Ref]

Hypersensitivity

Frequency not reported: Contact dermatitis, allergic conjunctivitis, eyelid edema^[Ref]

Respiratory

Severe reaction to the ointment may include hypotension with progressive respiratory depression. Coma and death have been reported in very young children.^[Ref]

Frequency not reported: Decreased bronchial secretions with dry throat and difficulty talking^[Ref]

Dermatologic

Frequency not reported: Dry skin, flushing, rash^[Ref]

Genitourinary

Frequency not reported: Urinary retention, urinary urgency

Local

Frequency not reported: Local irritation (with prolonged use)

Psychiatric

Frequency not reported: Confusion, delirium, hallucinations

Not all side effects for atropine ophthalmic may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

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