Anti-Diarrheal Side Effects
Generic Name: loperamide
Note: This document contains side effect information about loperamide. Some of the dosage forms listed on this page may not apply to the brand name Anti-Diarrheal.
For the Consumer
Applies to loperamide: oral capsule, oral capsule liquid filled, oral liquid, oral solution, oral suspension, oral tablet, oral tablet chewable
Along with its needed effects, loperamide (the active ingredient contained in Anti-Diarrheal) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking loperamide:Rare
Check with your doctor as soon as possible if any of the following side effects occur while taking loperamide:Rare
Some side effects of loperamide may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:Rare
- Dizziness or drowsiness
- dryness of mouth
For Healthcare Professionals
Applies to loperamide: compounding powder, oral capsule, oral liquid, oral suspension, oral tablet, oral tablet chewable
Common (1% to 10%): Constipation, nausea, flatulence, dry mouth, abdominal cramp, colic, vomiting, meteorism, abdominal pain
Uncommon (0.1% to 1%): Abdominal discomfort, abdominal pain upper, dyspepsia
Rare (less than 0.1%): Ileus (including paralytic ileus), megacolon (including toxic megacolon), abdominal distension[Ref]
Common (1% to 10%): Headache, dizziness
Uncommon (0.1% to 1%): Somnolence
Rare (less than 0.1%): Loss of consciousness, stupor, depressed level of consciousness, hypertonia, coordination abnormality
Postmarketing reports: Syncope[Ref]
Rare (less than 0.1%): Fatigue
Postmarketing reports: Death, tiredness[Ref]
Rare (less than 0.1%): Hypersensitivity reaction, anaphylactic reaction (including anaphylactic shock), anaphylactoid reaction[Ref]
Postmarketing reports: QT/QTc prolongation, Torsades de Pointes, other ventricular arrhythmias, cardiac arrest[Ref]
Rare (less than 0.1%): Miosis
1. "Product Information. Loperamide Hydrochloride (loperamide)." Teva Pharmaceuticals USA, North Wales, PA.
2. Walley T, Milson D "Loperamide related toxic megacolon in Clostridium difficile colitis." Postgrad Med J 66 (1990): 582
3. "Product Information. Imodium (loperamide)." Janssen Pharmaceutica, Titusville, NJ.
4. Brown JW "Toxic megacolon associated with loperamide therapy." JAMA 241 (1979): 501-2
5. Ericsson CD, Johnson PC "Safety and efficacy of loperamide." Am J Med 88 (1990): s10-4
6. Olm M, Gonzalez FJ, Garcia-Valdecasas JC, Fuster J, Bertran A, Milla J "Necrotising colitis with perforation in diarrhoic patients treated with loperamide." Eur J Clin Pharmacol 40 (1991): 415-6
7. Katz JP, Sturmann KM "Appendicitis associated with loperamide hydrochloride abuse." Ann Pharmacother 27 (1993): 369-70
8. Hill MA, Greason FC "Loperamide dependence." J Clin Psychiatry 53 (1992): 450
Some side effects of Anti-Diarrheal may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.
More about Anti-Diarrheal (loperamide)
- Side Effects
- During Pregnancy or Breastfeeding
- Dosage Information
- Drug Images
- Drug Interactions
- Support Group
- 2 Reviews – Add your own review/rating
- Drug class: antidiarrheals
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