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Acebutolol Side Effects

In Summary

Commonly reported side effects of acebutolol include: fatigue. Other side effects include: constipation, diarrhea, dizziness, dyspepsia, and nausea. See below for a comprehensive list of adverse effects.

For the Consumer

Applies to acebutolol: oral capsule, oral tablet

In addition to its needed effects, some unwanted effects may be caused by acebutolol. In the event that any of these side effects do occur, they may require medical attention.

Major Side Effects

You should check with your doctor immediately if any of these side effects occur when taking acebutolol:

Less common:
  • Changes in vision
  • chest pain
  • difficult or labored breathing
  • shortness of breath
  • swelling of face, fingers, feet, or lower legs
  • tightness in chest
  • wheezing

If any of the following symptoms of overdose occur while taking acebutolol, get emergency help immediately:

Symptoms of overdose:
  • Anxiety
  • blurred vision
  • chest discomfort
  • chills
  • cold sweats
  • coma
  • confusion
  • convulsions
  • cool, pale skin
  • cough
  • decreased urine output
  • depression
  • dilated neck veins
  • dizziness, faintness, or lightheadedness when getting up from a lying or sitting position suddenly
  • extreme fatigue
  • headache
  • increased hunger
  • irregular breathing
  • loss of bladder control
  • muscle spasm or jerking of all extremities
  • nausea
  • nervousness
  • nightmares
  • noisy breathing
  • pain in the shoulders, back, neck, or jaw
  • shakiness
  • slow, fast, pounding, or irregular heartbeat
  • slurred speech
  • sudden loss of consciousness
  • sweating
  • troubled breathing
  • unusual tiredness or weakness
  • weight gain

Minor Side Effects

Some of the side effects that can occur with acebutolol may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

Less common:
  • Acid or sour stomach
  • belching
  • bloated
  • diarrhea
  • difficulty having a bowel movement (stool)
  • difficulty in moving
  • discouragement
  • excess air or gas in stomach or intestines
  • feeling sad or empty
  • full feeling
  • heartburn
  • indigestion
  • irritability
  • lack of appetite
  • loss of interest or pleasure
  • muscle aching or cramping
  • muscle pain or stiffness
  • pain in joints
  • passing gas
  • problems in urination or increase in amount of urine
  • rash
  • sleeplessness
  • stomach discomfort, upset, or pain
  • swollen joints
  • tiredness
  • trouble concentrating
  • trouble sleeping
  • unable to sleep
  • unusual dreams

For Healthcare Professionals

Applies to acebutolol: compounding powder, oral capsule

General

The most common adverse reactions were fatigue and gastrointestinal disorders.[Ref]

Other

Very common (10% or more): Fatigue (11%)
Common (1% to 10%): Chest pain, edema
Frequency not reported: Lactate dehydrogenase (LDH) increased, alkaline phosphatase increased, fever, malaise, withdrawal syndrome[Ref]

Gastrointestinal

Common (1% to 10%): Constipation, diarrhea, dyspepsia, flatulence, nausea
Frequency not reported: Vomiting, abdominal pain[Ref]

Psychiatric

Common (1% to 10%): Depression, insomnia, abnormal dreams
Frequency not reported: Anxiety, psychoses, hallucination, confusion, loss of libido, sleep disorder[Ref]

Respiratory

Common (1% to 10%): Cough, dyspnea, rhinitis
Frequency not reported: Pharyngitis, wheezing, pneumonitis, lung infiltration[Ref]

Musculoskeletal

Common (1% to 10%): Arthralgia, myalgia
Uncommon (0.1% to 1%): Lupus like syndrome
Frequency not reported: Back pain, joint pain, systemic lupus erythematosus[Ref]

Nervous system

Common (1% to 10%): Dizziness, headache
Frequency not reported: Hyper/hypoesthesia, paresthesia[Ref]

Genitourinary

Common (1% to 10%): Micturition frequency
Frequency not reported: Impotence, dysuria, nocturia, dark urine[Ref]

Ocular

Common (1% to 10%): Abnormal vision
Frequency not reported: Conjunctivitis, dry eye, eye pain[Ref]

Dermatologic

Common (1% to 10%): Rash
Frequency not reported: Pruritus[Ref]

Cardiovascular

Frequency not reported: Hypotension, bradycardia, heart failure, first degree atrioventricular block, existing atrioventricular block increased, intermittent claudication, Raynaud's syndrome, cyanosis peripheral, peripheral coldness[Ref]

Hepatic

Frequency not reported: Serum glutamic oxaloacetic transaminase (SGOT) increased, serum glutamic pyruvic transaminase (SGPT) increased, bilirubin increased, hepatic enzymes increased, liver injury[Ref]

Immunologic

Frequency not reported: Antinuclear antibody[Ref]

Metabolic

Frequency not reported: Anorexia[Ref]

References

1. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

2. "Product Information. Sectral (acebutolol)." Wyeth-Ayerst Laboratories, Philadelphia, PA.

Not all side effects for acebutolol may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

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