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Acebutolol Dosage

Medically reviewed by Last updated on Aug 3, 2023.

Applies to the following strengths: 200 mg; 400 mg

Usual Adult Dose for Hypertension

Initial dose: 400 mg orally per day in 1 to 2 divided doses
Maintenance dose: 400 to 800 mg orally per day

Comments: Some patients may respond to as little as 200 mg orally per day; patients with inadequately controlled or more severe hypertension may respond to 600 mg orally twice a day or to the addition of a second antihypertensive; beta-1 selectivity diminishes with increasing dose.

Usual Adult Dose for Ventricular Arrhythmia

Initial dose: 200 mg orally twice a day
Maintenance dose: 600 to 1200 mg orally per day

Renal Dose Adjustments

CrCl less than 50 mL/min: Reduce daily dose by 50%
CrCl less than 25 mL/min: Reduce daily dose by 75%

Liver Dose Adjustments

Use with caution


Safety and efficacy have not been established in patients younger than 18 years.

Consult WARNINGS section for additional precautions.


Data not available

Other Comments

Patient advice:

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.