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Anticoagulant Sodium Citrate

Medically reviewed on Nov 15, 2018

Index Terms

  • AC
  • Trisodium Citrate

Dosage Forms

Excipient information presented when available (limited, particularly for generics); consult specific product labeling.

Concentrate, In Vitro:

TriCitrasol: 46.7% (30 mL)

Solution, In Vitro:

Generic: 4% (250 mL, 500 mL)

Brand Names: U.S.

  • TriCitrasol

Pharmacologic Category

  • Anticoagulant

Use: Labeled Indications


Concentrate (triCitrasol): Anticoagulant used in granulocytapheresis procedures

Solution: Anticoagulant for use with cytapheresis device only


Direct intravenous infusion


Concentrate: Store at 24°C (75°F); excursions permitted to 15°C to 30°C (59°F to 86°F). Protect from freezing and excessive heat. Discard if solution becomes cloudy.

Solution: Store at room temperature. Do not remove from overlap until ready to use. Discard if solution becomes cloudy. Discard any unused portion.

Drug Interactions

There are no known significant interactions.

Adverse Reactions

Frequency not defined:

Cardiovascular: Cardiac arrhythmia, chest pressure, hypotension

Central nervous system: Chills, paresthesia, tingling in the lips, tingling of extremities

Gastrointestinal: Stomach cramps


Other warnings/precautions:

• Appropriate use: Concentrate: Not for direct intravenous infusion into patients; for use in granulocytapheresis procedures only.

• Appropriate use: Solution: Not for direct intravenous infusion into patients; to be used with cytapheresis device only.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.