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Latanoprost and netarsudil ophthalmic

Generic Name: latanoprost and netarsudil ophthalmic (la TAN oh prost and ne TAR soo dil off THAL mik)
Brand Name: Rocklatan

Medically reviewed by Drugs.com on May 1, 2019 – Written by Cerner Multum

What is latanoprost and netarsudil ophthalmic?

Latanoprost and netarsudil ophthalmic (for the eyes) is a combination medicine used to treat open-angle glaucoma and other causes of high pressure inside the eye.

Latanoprost and netarsudil ophthalmic may also be used for purposes not listed in this medication guide.

Important Information

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

Before taking this medicine

You should not use latanoprost and netarsudil ophthalmic if you are allergic to latanoprost or netarsudil.

Tell your doctor if you have ever had:

  • swelling or an infection in your eye;

  • damage to the surface of your eye (also called the cornea);

  • herpes infection of the eyes; or

  • eye surgery or injury affecting the lens of your eye.

Latanoprost can cause a gradual change in the color of your eyes or eyelids and lashes, usually an increase in brown pigment. You may also notice increased growth or thickness of your eyelashes. These changes occur slowly and you may not notice them for months or years. Color changes may be permanent even after your treatment ends, and may occur only in the eye being treated. This could result in a cosmetic difference in eye or eyelash color from one eye to the other.

Latanoprost and netarsudil ophthalmic is not approved for use by anyone younger than 18 years old.

Tell your doctor if you are pregnant or breast-feeding.

How should I use latanoprost and netarsudil ophthalmic?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

The usual dose of this medicine is 1 drop into the affected eye every evening. Follow your doctor's dosing instructions very carefully.

Do not use while wearing soft contact lenses. A preservative in this medicine could permanently stain the lenses. Use the medicine at least 15 minutes before inserting your contact lenses.

Wash your hands before using eye medication.

To apply the eye drops: Tilt your head back slightly and pull down your lower eyelid to create a small pocket. Hold the dropper above the eye and squeeze a drop into this pocket. Close your eyes for 1 or 2 minutes.

Use only the number of drops your doctor has prescribed.

Wait at least 5 minutes before using any other eye drops your doctor has prescribed.

Do not touch the tip of the eye dropper or place it directly on your eye. A contaminated dropper can infect your eye, which could lead to serious vision problems.

Tell your doctor right away if you have an eye injury or eye infection, or if you plan to have eye surgery.

Store in the refrigerator. Protect from light and do not freeze. Keep the bottle tightly closed when not in use.

What happens if I miss a dose?

Skip the missed dose and use the medicine at the next regularly scheduled time. Do not use extra medicine to make up the missed dose.

What happens if I overdose?

An overdose of latanoprost and netarsudil ophthalmic is not expected to be dangerous. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222 if anyone has accidentally swallowed the medication.

What should I avoid while using latanoprost and netarsudil ophthalmic?

Avoid using too much of latanoprost and netarsudil ophthalmic, which can actually make it less effective in lowering the pressure inside the eye.

Do not use other eye medications unless your doctor tells you to.

Latanoprost and netarsudil ophthalmic side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using latanoprost and call your doctor at once if you have:

  • eye swelling, redness, severe discomfort, crusting or drainage (may be signs of infection);

  • red, swollen, or itchy eyelids;

  • vision changes; or

  • severe burning, stinging, or irritation after using this medicine.

Common side effects may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Latanoprost and netarsudil ophthalmic dosing information

Usual Adult Dose for Intraocular Hypertension:

Latanoprost 0.005%-netarsudil 0.02% ophthalmic solution: 1 drop into the affected eye(s) once a day in the evening
-Maximum dose: 1 drop/eye/day

Comment: Administration of other topical ophthalmic drugs to lower intraocular pressure (IOP) should be separated by at least 5 minutes.

Use: Reduction of elevated IOP in patients with open-angle glaucoma or ocular hypertension

Usual Adult Dose for Glaucoma (Open Angle):

Latanoprost 0.005%-netarsudil 0.02% ophthalmic solution: 1 drop into the affected eye(s) once a day in the evening
-Maximum dose: 1 drop/eye/day

Comment: Administration of other topical ophthalmic drugs to lower intraocular pressure (IOP) should be separated by at least 5 minutes.

Use: Reduction of elevated IOP in patients with open-angle glaucoma or ocular hypertension

What other drugs will affect latanoprost and netarsudil ophthalmic?

Medicine used in the eyes is not likely to be affected by other drugs you use. But many drugs can interact with each other. Tell each of your healthcare providers about all medicines you use, including prescription and over-the-counter medicines, vitamins, and herbal products.

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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