Hydrochlorothiazide and telmisartan
Generic Name: hydrochlorothiazide and telmisartan (HYE droe KLOR oh THYE a zide and TEL mi SAR tan)
Brand Name: Micardis HCT
Medically reviewed on July 18, 2017.
What is hydrochlorothiazide and telmisartan?
Hydrochlorothiazide is a thiazide diuretic (water pill) that helps prevent your body from absorbing too much salt, which can cause fluid retention.
Telmisartan is an angiotensin II receptor antagonist. Telmisartan keeps blood vessels from narrowing, which lowers blood pressure and improves blood flow.
Hydrochlorothiazide and telmisartan may also be used for purposes not listed in this medication guide.
Do not use if you are pregnant. If you become pregnant, stop taking this medicine and tell your doctor right away.
You should not use this medicine if you are unable to urinate.
Before taking this medicine
You should not use this medicine if you are allergic to hydrochlorothiazide or telmisartan, if you are unable to urinate.
If you have diabetes, do not use hydrochlorothiazide and telmisartan together with any medication that contains aliskiren (such as Tekturna or Tekamlo).
You may also need to avoid taking hydrochlorothiazide and telmisartan with aliskiren if you have kidney disease.
To make sure hydrochlorothiazide and telmisartan is safe for you, tell your doctor if you have ever had:
congestive heart failure;
low or high levels of magnesium or potassium in your blood;
an allergy to penicillin or sulfa drugs.
Do not use if you are pregnant. If you become pregnant, stop taking this medicine and tell your doctor right away. Hydrochlorothiazide and telmisartan can cause injury or death to the unborn baby if you take the medicine during your second or third trimester.
Hydrochlorothiazide can pass into breast milk and may cause side effects in the nursing baby. You should not breast-feed while using this medicine.
How should I take hydrochlorothiazide and telmisartan?
Follow all directions on your prescription label. Your doctor may occasionally change your dose. Do not take this medicine in larger or smaller amounts or for longer than recommended.
You may take this medicine with or without food.
Your blood pressure will need to be checked often.
Call your doctor if you have ongoing vomiting or diarrhea, or if you are sweating more than usual. You can easily become dehydrated while taking this medication, which can lead to severely low blood pressure or a serious electrolyte imbalance.
If you need surgery or medical tests, tell the surgeon ahead of time that you are using hydrochlorothiazide and telmisartan.
It may take up to 4 weeks for this medication to control your blood pressure. Keep using this medicine as directed, even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medication for the rest of your life.
Read all patient information, medication guides, and instruction sheets provided to you. Ask your doctor or pharmacist if you have any questions.
Store at room temperature away from moisture and heat. Keep each tablet in its blister pack until you are ready to take it. Gently push the tablet through the foil to remove it.
What happens if I miss a dose?
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
Overdose symptoms may include fast or slow heart rate, feeling light-headed, or fainting.
What should I avoid while taking hydrochlorothiazide and telmisartan?
Do not use potassium supplements or salt substitutes while you are taking hydrochlorothiazide and telmisartan, unless your doctor has told you to.
Drinking alcohol can further lower your blood pressure and may cause side effects.
Avoid becoming overheated or dehydrated during exercise, in hot weather, or by not drinking enough fluids.
Hydrochlorothiazide and telmisartan side effects
Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
In rare cases, hydrochlorothiazide and telmisartan can cause a condition that results in the breakdown of skeletal muscle tissue, leading to kidney failure. Call your doctor right away if you have unexplained muscle pain, tenderness, or weakness especially if you also have fever, unusual tiredness, and dark colored urine.
Also call your doctor at once if you have:
eye pain, vision problems;
a light-headed feeling, like you might pass out;
jaundice (yellowing of the skin or eyes);
easy bruising, unusual bleeding;
kidney problems--little or no urination, painful or difficult urination, swelling in your feet or ankles, feeling tired or short of breath;
lupus-like syndrome--joint pain or swelling with fever, swollen glands, muscle aches, chest pain, vomiting, unusual thoughts or behavior, and patchy skin color; or
signs of an electrolyte imbalance--dry mouth, increased thirst, drowsiness, confusion, feeling restless, vomiting, muscle pain or weakness, lack of energy, fast heartbeats, little or no urine, or a seizure.
Common side effects may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
See also: Side effects (in more detail)
Hydrochlorothiazide and telmisartan dosing information
Usual Adult Dose for Hypertension:
Hydrochlorothiazide 12.5 to 25 mg-Telmisartan 80 mg orally once a day
Maximum dose: Hydrochlorothiazide 25 mg-Telmisartan 160 mg orally once a day
-This drug may be substituted for the individual titrated components.
-If blood pressure remains uncontrolled by hydrochlorothiazide 25 mg orally once a day monotherapy, may switch to hydrochlorothiazide 12.5 to 25 mg-telmisartan 80 mg orally once a day. Reassess after 2 to 4 weeks; may increase up to hydrochlorothiazide 25 mg-telmisartan 160 mg orally once a day.
-If blood pressure is controlled by hydrochlorothiazide 25 mg orally once a day monotherapy, but hypokalemia occurs, may switch to hydrochlorothiazide 12.5 mg-telmisartan 80 mg orally once a day.
-If blood pressure remains uncontrolled by telmisartan 80 mg orally once a day monotherapy, may switch to hydrochlorothiazide 12.5 mg-telmisartan 80 mg orally once a day; may titrate up to hydrochlorothiazide 25 mg-telmisartan 160 mg orally once a day, if necessary.
Use: Treatment of hypertension; not indicated for initial therapy.
What other drugs will affect hydrochlorothiazide and telmisartan?
Tell your doctor about all your current medicines and any you start or stop using, especially:
any other heart or blood pressure medications;
a diuretic or "water pill";
insulin or oral diabetes medicine;
opioid (narcotic) pain medicine;
a sleeping pill;
steroid medicine (ACTH);
This list is not complete. Other drugs may interact with hydrochlorothiazide and telmisartan, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Copyright 1996-2018 Cerner Multum, Inc. Version: 8.01.
More about hydrochlorothiazide/telmisartan
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- Drug class: angiotensin II inhibitors with thiazides
Other brands: Micardis HCT