What is 1-Day?
Tioconazole is an antifungal medication that fights infections caused by fungus.
1-Day (for use in the vagina) is used to treat vaginal Candida (yeast) infections.
1-Day may also be used for other purposes not listed in this medication guide.
Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.
Before taking this medicine
You should not use 1-Day if you are allergic to it.
Do not use this medicine if you have never had a vaginal yeast infection that has been confirmed by a doctor.
Ask a doctor or pharmacist if it is safe for you to use this medicine if you have other medical conditions, especially:
if you are having vaginal itching or discomfort for the first time; or
if you think you may have been exposed to HIV (human immunodeficiency virus).
FDA pregnancy category C. It is not known whether 1-Day will harm an unborn baby. Do not use this medicine without your doctor's advice if you are pregnant.
It is not known whether 1-Day passes into breast milk or if it could harm a nursing baby. Do not use this medicine without your doctor's advice if you are breast-feeding.
Do not give this medication to anyone under 12 years old without medical advice.
How should I use 1-Day?
Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.
Do not take 1-Day by mouth. It is for use only in your vagina.
This medication comes with patient instructions for safe and effective use. Follow these directions carefully. Ask your doctor or pharmacist if you have any questions.
This medicine is usually given as a single dose. You should notice some improvement in your symptoms after the 1-day treatment. It may take up to 7 days after using the 1-day dose before your symptoms go away completely.
Call your doctor if your symptoms do not improve after 3 days, or if you still have symptoms for longer than 7 days. Frequent vaginal yeast infections that do not clear up with treatment may be a sign of a more serious condition.
The single-use applicator is for one use only. Throw the applicator away after one use, even if there is still some medicine left in it after inserting your dose.
1-Day contains mineral oil or petrolatum, which can weaken the latex rubber in a condom or diaphragm. These forms of birth control may be less effective if you use them during your treatment with this medicine. Use another form of birth control while you are using tioconazole and for at least 3 full days after your treatment ends.
Store at room temperature away from moisture and heat. Do not warm the medicine applicator before using 1-Day.
What happens if I miss a dose?
Since 1-Day is used as a single dose, it does not have a daily dosing schedule.
What happens if I overdose?
Since 1-Day is used as a single dose from a prefilled applicator, an overdose is unlikely to occur.
What should I avoid while using 1-Day?
Avoid wearing tight-fitting, synthetic clothing such as nylon underwear or panty hose that does not allow air circulation. Wear loose-fitting clothing made of cotton and other natural fibers until your infection is healed.
Do not use a tampon, vaginal douche, spermicide, or other vaginal products while you are using 1-Day. Do not have vaginal intercourse during treatment.
1-Day side effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have new or worsening vaginal symptoms.
Common side effects may include:
vaginal redness or swelling;
mild stomach pain;
pain or burning when you urinate;
headache, runny or stuffy nose; or
mild vaginal burning, itching or irritation after use.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
See also: Side effects (in more detail)
What other drugs will affect 1-Day?
It is not likely that other drugs you take orally or inject will have an effect on tioconazole used in the vagina. But many drugs can interact with each other. Tell each of your healthcare providers about all medicines you use, including prescription and over-the-counter medicines, vitamins, and herbal products.
More about Tioconazole 1 Day (tioconazole topical)
- Side Effects
- During Pregnancy or Breastfeeding
- Dosage Information
- En Español
- 19 Reviews – Add your own review/rating
Other brands: Vagistat-1
Related treatment guides
Where can I get more information?
- Your pharmacist can provide more information about 1-Day.
- Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
- Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2012 Cerner Multum, Inc. Version: 6.03.
Date modified: March 06, 2018
Last reviewed: February 05, 2014