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Can you drink alcohol while taking Skyrizi?

Medically reviewed by Carmen Pope, BPharm. Last updated on Aug 7, 2024.

Official Answer by Drugs.com

Skyrizi (risankizumab-rzaa) is a medication used to treat adults with moderate-to-severe plaque psoriasis who are candidates for systemic therapy or phototherapy, as well as adults with active psoriatic arthritis or moderately-to-severely active ulcerative colitis or Crohn's disease. Skyrizi is not known to interact with alcohol and there is no warning in the Skyrizi Package Insert against drinking alcohol while receiving Skyrizi.

While drinking alcohol isn’t contraindicated while Skyrizi is being used as a treatment, alcohol consumption is known to be higher in people with psoriasis than the general population and drinking alcohol can worsen the symptoms of psoriasis. People with psoriasis may benefit from limiting or avoiding alcohol. Alcohol consumptions should also be limited or avoided in people with ulcerative colitis or Crohn's disease if if causes symptoms to flare up.

References
  • Skyrizi Prescribing Information. Revised 06/2024. AbbVie Inc. https://www.rxabbvie.com/pdf/skyrizi_pi.pdf
  • Skyrizi Package Insert. Revised 06/2024. AbbVie Inc. https://www.rxabbvie.com/pdf/skyrizi_medguide.pdf
  • Brenaut E, Horreau C, Pouplard C, et al. Alcohol consumption and psoriasis: a systematic literature review. J Eur Acad Dermatol Venereol. 2013;27 Suppl 3:30-35. doi:10.1111/jdv.12164.
  • Szentkereszty-Kovács Z, Gáspár K, Szegedi A, Kemény L, Kovács D, Törőcsik D. Alcohol in Psoriasis-From Bench to Bedside. Int J Mol Sci. 2021;22(9):4987. Published 2021 May 7. doi:10.3390/ijms22094987.
  • Piovezani Ramos G, Kane S. Alcohol Use in Patients With Inflammatory Bowel Disease. Gastroenterol Hepatol (N Y). 2021;17(5):211-225.
  • FDA Approves Skyrizi (risankizumab-rzaa) for Ulcerative Colitis. June 18, 2024. Drugs.com https://www.drugs.com/newdrugs/fda-approves-skyrizi-risankizumab-rzaa-ulcerative-colitis-6307.html

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