How well does Trogarzo work to treat multidrug-resistant (MDR) HIV-1?
Medically reviewed by Drugs.com. Last updated on Sep 30, 2024.
Trogarzo (ibalizumab-uiyk) was studied in a clinical trial of 40 multidrug-resistant (MDR) HIV-1 infection patients with high HIV virus levels. These patients had already received multiple other HIV treatments (some patients had received 10 or more). Most patients (33 of the 40 patients, or 83%) experienced a significant decrease in their HIV-RNA levels one week after Trogarzo was added to their ineffective antiretroviral regimens. After 24 weeks of Trogarzo plus other antiretroviral drugs, 43% of the trial’s participants achieved HIV RNA suppression.
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Which medicines should not be taken with Biktarvy?
- Biktarvy is a complete regimen and use with other antiretroviral medications for the treatment of HIV-1 infection is not recommended.
- Biktarvy is associated with many drug interactions as it contains three different medicines, increasing your risk for interactions. Have your health care provider check for possible interactions with other prescription medicines, OTCs or herbal you take.
- You should not take Biktarvy with dofetilide (Tikosyn), a drug used for heart rhythm disorders or rifampin (Rifadin), a medicine for tuberculosis (TB). These drugs are contraindicated with the use of Biktarvy.
Who are the actors in the Dovato commercial?
Three real-life patients feature in the Dovato commercial “Detect This” released on May 23, 2022. They are Jovon [surname withheld], Ann Edwards, and Armando [surname withheld]. Continue reading
Descovy vs Truvada: How do they compare for HIV / PrEP?
Truvada and Descovy are both two-drug, antiviral combinations containing emtricitabine and tenofovir for the treatment of HIV-1 infection, and for pre-exposure prophylaxis (PrEP) to reduce the risk of HIV-1 infection. Descovy contains a newer form of tenofovir called tenofovir alafenamide (TAF) and Truvada contains the original form of tenofovir as tenofovir disoproxil fumarate (TDF). TAF has less toxicities related to bone and kidneys. Continue reading
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