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How is Trogarzo used in the treatment of HIV?

Medically reviewed by Last updated on Oct 8, 2019.

Official Answer


Trogarzo (ibalizumab-uiyk) is used to treat the small percentage of patients who have multidrug-resistant human immunodeficiency virus type 1 HIV (MDR HIV-1 Infection) and who have failed other HIV therapies.

Trogarzo is a first-in-class CD4-directed post-attachment HIV-1 inhibitor that works by binding to CD4+ receptors on host cells and blocking the HIV virus from infecting the cells. It is the first monoclonal antibody approved for the treatment of MDR HIV-1 infection, and is used in combination with other antiretroviral drugs.

Trogarzo is administered intravenously (IV) once every 14 days by a trained medical professional.

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