Who makes Imbruvica?
- Imbruvica is made by Pharmacyclics LLC which is a company that was acquired by AbbVie in 2015.
- Imbruvica is marketed by Abbive in the United States and by Janssen in Europe, the Middle East and Africa.
The compound that was to later become known as Imbruvica was created by scientists at Celera Genomics as a compound for studying the function of the enzyme, Bruton tyrosine kinase (BTK).
In 2006, Pharmacyclics acquired the compound alongside a few other development programs, and renamed the compound PCI-32765.
In 2011 after the drug had completed Phase II trials, Pharmacyclics and Johnson & Johnson agreed to co-develop the drug, and J&J paid Pharmacyclics $150 million upfront and $825 million in milestones.
In 2015, Pharmacyclics was acquired by AbbVie in May 2015 for $21 million, and currently, Imbruvica is co-marketed by Janssen – a pharmaceutical company belonging to Johnson & Johnson; and Abbvie.
The Pharmacyclics name was retained, and it operates as a subsidiary of AbbVie from its previous Sunnyvale, California, headquarters.
Janssen markets Imbruvica in Europe, the Middle East and Africa and AbbVie markets it in the United States.
In 2018, Imbruvica generated a total of $5.6 billion for Janssen and AbbVie and is forecast to generate $11.9 billion in 2025.
References
- Imbruvica (ibrutinib) capsules [Package Insert] Pharmacyclics LLC, an AbbVie Company and Janssen Biotech, Inc https://www.drugs.com/pro/imbruvica.html
- Janssen and AbbVie’s Imbruvica earns approval in two new settings from the EC Pharmaceutical-Technology 08/2019 https://www.pharmaceutical-technology.com/comment/janssen-and-abbvie-imbruvica-2019/
Read next
How much does Imbruvica cost?
According to the Drugs.com price guide which bases its price on the Drugs.com discount card which is accepted at most U.S. pharmacies, the cost for Imbruvica 420mg tablet is around $616 per tablet or $17 269 for a supply of 28 tablets depending on the pharmacy you visit. Prices are for cash paying customers only and are not valid with insurance plans. Continue reading
How long can you stay on Imbruvica (ibrutinib)?
Imbruvica (ibrutinib) is usually continued indefinitely if it is being well tolerated, there is limited disease progression, and toxicity has not occurred. Continue reading
Can ibrutinib be stopped safely?
Stopping ibrutinib can result in a disease flare-up in patients with chronic lymphocytic leukemia (CLL). A 2020 study in The Oncologist found that approximately 25% of ibrutinib patients with a median interruption period of 8 days experienced a flare or rapid CLL progression. Continue reading
See also:
Aimovig
Learn about Aimovig (erenumab-aooe) a once-monthly, injectable medication that can be ...
Nurtec ODT
Nurtec ODT (rimegepant) is used to treat acute migraines and prevent episodic migraines, by ...
Botox
Botox is used cosmetically to reduce facial lines and wrinkles and for medical purposes for ...
Depakote
Depakote is used to treat various types of seizure disorders. Learn about side effects ...
Topamax
Topamax (topiramate) is used to prevent seizures in adults and children and to prevent migraine ...
Emgality
Emgality (galcanezumab-gnlm) is a CGRP antagonist for the preventive treatment of migraine and for ...
Timolol
Timolol is used for angina, heart attack, high blood pressure, migraine, migraine prevention
Valproic acid
Valproic acid is used for bipolar disorder, cluster-tic syndrome, epilepsy, headache ...
Divalproex sodium
Divalproex sodium is used for bipolar disorder, borderline personality disorder, cyclothymic ...
Propranolol
Propranolol is a beta-blocker that is used to treat tremors, chest pain, high blood pressure, heart ...
Related medical questions
- How quickly does Imbruvica (ibrutinib) work?
- Acalabrutinib vs. ibrutinib: How do they compare?
- Does ibrutinib cause hair loss?
- Is Imbruvica a chemotherapy drug?
- What are the names of the BTK inhibitors?
- How to apply for and use the Imbruvica copay card?
- Prednisone: What are 12 Things You Should Know?
- What is the success rate of Keytruda?
- What is CAR T-cell therapy and how does it work?
- What is ABVD chemo regimen and how is it used for lymphoma?
- Is Velcade a type of chemotherapy?
- How long does Velcade stay in your body?
- What is the cost of Yescarta?
- How and where is Adcetris administered?
- Is Adcetris a chemotherapy drug?
- How to pronounce Xalkori?
- How long does it take for Xalkori to work?
- Who makes Leukeran, and where is it made?
- What cancers are treated with Xalkori?
- How is Yescarta administered?
- What type of drug is Yescarta (axicabtagene ciloleucel)?