How does Lucemyra work in the treatment of opioid withdrawal?
Medically reviewed by Drugs.com. Last updated on May 30, 2022.

Official answer
by Drugs.comLucemyra (lofexidine hydrochloride) is an oral, selective alpha 2-adrenergic receptor agonist and works by reducing the release of norepinephrine. The actions of norepinephrine, a central nervous system chemical messenger (neurotransmitter), are believed to play a role in many of the symptoms of opioid withdrawal.
Opioid withdrawal symptoms may include:
- anxiety
- agitation
- sleep problems
- muscle aches
- runny nose
- sweating
- nausea and vomiting
- diarrhea
- drug craving
Related medical questions
- How does Lucemyra make you feel?
- How do you get Lucemyra (lofexidine)?
- Is Lucemyra (lofexidine) a controlled drug?
- How long does lofexidine typically take to work?
Drug information
- Lucemyra Information for Consumers
- Lucemyra Information for Healthcare Professionals (includes dosage details)
- Side Effects of Lucemyra (detailed)
Related support groups
- Lucemyra (4 questions, 6 members)
- Opiate Withdrawal (53 questions, 2331 members)