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How does Lucemyra work in the treatment of opioid withdrawal?

Medically reviewed by Drugs.com. Last updated on May 30, 2023.

Official answer

by Drugs.com

Lucemyra (lofexidine hydrochloride) is an oral, selective alpha 2-adrenergic receptor agonist and works by reducing the release of norepinephrine. The actions of norepinephrine, a central nervous system chemical messenger (neurotransmitter), are believed to play a role in many of the symptoms of opioid withdrawal.

Opioid withdrawal symptoms may include:

  • anxiety
  • agitation
  • sleep problems
  • muscle aches
  • runny nose
  • sweating
  • nausea and vomiting
  • diarrhea
  • drug craving

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