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How long does ciprofloxacin stay in your system when finished?

Medically reviewed by Last updated on Aug 18, 2023.

Official answer


Ciprofloxacin should be out of your system around 22 hours after your last dose. The serum elimination half-life of ciprofloxacin with normal kidney function is approximately 4 hours. This is the time it takes for your body to reduce the plasma levels by half. It usually takes around 5.5 x half-lifes for a drug to be completely eliminated from your system (5.5 x 4= 22 hours).

Other factors also need to be taken into account and include:

  1. How much and how often you have taken the drug.
  2. Your metabolic rate – a slower metabolism will increase the time a drug remains in your system.
  3. Your age and health – older age and poor health will generally increase the time the drug stays in your system.
  4. Body mass – generally the bigger you are the longer a drug will remain in your system.

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