Can I take Gleevec while pregnant?
No, you should NOT take Gleevec (generic name: imatinib) if you are pregnant or could become pregnant. Taking Gleevec while you are pregnant could harm an unborn baby. You may need to have a negative pregnancy test before starting this treatment.
Use effective birth control (contraception) to prevent pregnancy while you are using this medicine and for at least 14 days after your last dose. Use a birth control method that results in a less than 1% pregnancy rate. Talk to your doctor for further advice on the most effective birth control options.
Based on human and animal data from the manufacturer of Gleevec, this drug can cause fetal harm when administered to a pregnant woman. Do not become pregnant while taking Gleevec.
If you are pregnant, planning a pregnancy or breastfeeding tell your doctor. Talk to your doctor right away if you think you are, or might be pregnant. Always follow your doctor's instructions exactly during treatment with Gleevec.
Can I breastfeed with Gleevec?
Do not breastfeed a baby while you are using Gleevec and for at least 1 month after you take your last dose of Gleevec. Gleevec can get into your breast milk. There is a possibility of bad (serious) side effects in the baby.
Always consult your doctor or healthcare specialist for medical advice in relation to drug use while pregnant or breastfeeding. Prescribing should be made on a case-by-case basis, and information may not be applicable to every situation.
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Imkeldi
In November 2024, a new formulation of imatinib (the active ingredient in Gleevec tablets), was approved by the FDA. The new formulation is an oral solution of imatinib known as Imkeldi.
Imkeldi has the same pregnancy and breastfeeding warnings and precautions as Gleevec because it contains the same active ingredient. Imkeldi can cause fetal harm when administered to a pregnant woman.
If you are pregnant, planning a pregnancy or breastfeeding tell your doctor before you are prescribed or start taking Gleevec or Imkeldi.
Related: Imatinib (Gleevec) Pregnancy and Breastfeeding Warnings
This is not all the information you need to know about Gleevec / Imkeldi (imatinib) for safe and effective use and does not take the place of your doctor's directions. Review the full product information, and discuss this information and any questions you have with your doctor or other health care provider.
References
- Imkeldi (imatinib) [product information]. 11/2024. Shorla Oncology. Accessed Nov 26, 2024 at https://shorlaoncology.com/pdf/Imkeldi_PrescribingInformation.pdf
- Gleevec (imatinib) [product information]. Revised 8/2020. Novartis Pharmaceuticals Corporation. East Hanover, NJ. Accessed Feb. 22, 2020 at https://www.novartis.us/sites/www.novartis.us/files/gleevec_tabs.pdf
- Gleevec.com. Important Safety Information: Who Should Not Take Gleevec. (online). Novartis Pharmaceuticals Corporation. East Hanover, NJ. Accessed Feb. 22, 2020 at https://www.us.gleevec.com/
- Contraception. US Centers for Disease Control and Prevention (CDC). 2024. Accessed Oct 24, 2024 at https://www.cdc.gov/contraception
- Imatinib Pregnancy and Breastfeeding Warnings. Drugs.com. Last updated on May 14, 2020. Accessed Feb. 21, 2021 at https://www.drugs.com/pregnancy/imatinib.html
Read next
How does Gleevec (imatinib) work?
Gleevec, known generically as imatinib, works by slowing or stopping the growth of certain cancer cells. Gleevec inhibits (or blocks) specific enzymes in the body called tyrosine kinases. Tyrosine kinases are involved in many cell functions, including cell signaling (communication), growth, and division. Blocking these enzymes may help to slow cancer growth. Continue reading
Is Sprycel a chemotherapy drug?
Sprycel (dasatinib) is an oral targeted anticancer therapy classified as a tyrosine kinase inhibitor (TKI). It used to treat some types of blood cancer, such as Philadelphia chromosome-positive (Ph+) chronic myeloid leukemia (Ph+ CML) or acute lymphoblastic leukemia (Ph+ ALL). Continue reading
What happens if you take Tasigna with food?
If you take Tasigna with food, it may increase the absorption of the medicine into your blood and may increase your chances for a serious abnormal heart rhythm (QTc prolongation) that could lead to sudden death. Do not eat any food for at least 2 hours before your dose and for at least 1 hour after your dose is taken. Continue reading
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