Drug Interaction Report
8 potential interactions and/or warnings found for the following 2 drugs:
- cimetidine
- Genvoya (cobicistat / elvitegravir / emtricitabine / tenofovir alafenamide)
Interactions between your drugs
cimetidine tenofovir
Applies to: cimetidine, Genvoya (cobicistat / elvitegravir / emtricitabine / tenofovir alafenamide)
Using tenofovir together with cimetidine can increase the blood levels and effects of both medications. Contact your doctor if your condition changes or you experience increased side effects, especially kidney problems. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. You should seek immediate medical attention if you develop signs and symptoms that may suggest kidney damage such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
tenofovir cobicistat
Applies to: Genvoya (cobicistat / elvitegravir / emtricitabine / tenofovir alafenamide), Genvoya (cobicistat / elvitegravir / emtricitabine / tenofovir alafenamide)
Using cobicistat together with tenofovir can increase the effects of tenofovir, which can cause new or worse kidney problems. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if your condition changes or you experience increased side effects. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
emtricitabine cobicistat
Applies to: Genvoya (cobicistat / elvitegravir / emtricitabine / tenofovir alafenamide), Genvoya (cobicistat / elvitegravir / emtricitabine / tenofovir alafenamide)
Cobicistat is a medication used to boost the effects of some medications that treat HIV infection. However, using cobicistat together with other HIV medications, such as emtricitabine, may alter the blood levels and effects of both medications. Using emtricitabine with cobicistat may reduce or increase blood levels of cobicistat. Reduced blood levels of cobicistat may make cobicistat less effective and may cause overall HIV treatment to be less effective. Cobicistat may increase blood levels of emtricitabine which may increase the risk of side effects. Talk to your doctor or pharmacist if you have any questions on how to use these medications properly. Your doctor may be able to prescribe alternatives that do not interact, or you may need a dose adjustment or more frequent monitoring to safely use both medications. Contact your doctor if your condition changes or you experience increased side effects. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Drug and food interactions
elvitegravir food
Applies to: Genvoya (cobicistat / elvitegravir / emtricitabine / tenofovir alafenamide)
Food significantly increases the absorption of elvitegravir. You should take each dose of elvitegravir with a meal. Taking it on an empty stomach may lead to inadequate blood levels and reduced effectiveness of the medication in treating HIV infection.
tenofovir food
Applies to: Genvoya (cobicistat / elvitegravir / emtricitabine / tenofovir alafenamide)
Information for this minor interaction is available on the professional version.
cimetidine food
Applies to: cimetidine
Information for this minor interaction is available on the professional version.
cimetidine food
Applies to: cimetidine
Information for this minor interaction is available on the professional version.
cimetidine food
Applies to: cimetidine
Information for this minor interaction is available on the professional version.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
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Magnesium oxide
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Calcium carbonate
Calcium carbonate is used for duodenal ulcer, erosive esophagitis, GERD, hypocalcemia, indigestion ...
Ranitidine
Ranitidine is used to treat and prevent ulcers in the stomach and intestines. Includes ranitidine ...
Lansoprazole
Lansoprazole is used to treat stomach and intestinal ulcers, erosive esophagitis and ...
Sucralfate
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Further information
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