Drug Interaction Report

Using sucralfate together with sodium bicarbonate can decrease the effects of sucralfate. Sucralfate and sodium bicarbonate doses should be separated by at least half an hour. You may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

When sucralfate is given with enteral (tube) feedings, the feeding tube may become clogged and/or sucralfate may not work as well. You could interrupt the feeding for 1 hour before and after the sucralfate dose. However, this still may not entirely avoid the interaction and may not always be feasible. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.