Acetaminophen Interactions
There are 160 drugs known to interact with acetaminophen, along with 3 disease interactions, and 2 alcohol/food interactions. Of the total drug interactions, 8 are major, 116 are moderate, and 36 are minor.
- View all 160 medications that may interact with acetaminophen
- View acetaminophen alcohol/food interactions (2)
- View acetaminophen disease interactions (3)
Most frequently checked interactions
View interaction reports for acetaminophen and the medicines listed below.
- Aspirin Low Strength (aspirin)
- Aspirin Low Strength (aspirin)
- Benadryl (diphenhydramine)
- Benadryl (diphenhydramine)
- CoQ10 (ubiquinone)
- CoQ10 (ubiquinone)
- Cymbalta (duloxetine)
- Cymbalta (duloxetine)
- Eliquis (apixaban)
- Eliquis (apixaban)
- Fish Oil (omega-3 polyunsaturated fatty acids)
- Fish Oil (omega-3 polyunsaturated fatty acids)
- Flonase (fluticasone nasal)
- Flonase (fluticasone nasal)
- Metoprolol Succinate ER (metoprolol)
- Metoprolol Succinate ER (metoprolol)
- Metoprolol Tartrate (metoprolol)
- Metoprolol Tartrate (metoprolol)
- MiraLAX (polyethylene glycol 3350)
- MiraLAX (polyethylene glycol 3350)
- Synthroid (levothyroxine)
- Synthroid (levothyroxine)
- Vitamin B12 (cyanocobalamin)
- Vitamin B12 (cyanocobalamin)
- Vitamin C (ascorbic acid)
- Vitamin C (ascorbic acid)
- Vitamin D3 (cholecalciferol)
- Vitamin D3 (cholecalciferol)
- Zyrtec (cetirizine)
- Zyrtec (cetirizine)
Acetaminophen alcohol/food interactions
There are 2 alcohol/food interactions with acetaminophen.
Acetaminophen disease interactions
There are 3 disease interactions with acetaminophen which include:
More about acetaminophen
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- Patient tips
- During pregnancy
- Support group
- Drug class: miscellaneous analgesics
- Breastfeeding
Related treatment guides
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
See also:
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Tylenol
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Caplyta
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Flexeril
Flexeril (cyclobenzaprine) is a muscle relaxant used to treat skeletal muscle conditions such as ...
Advil
Advil (ibuprofen) reduces fever, pain and inflammation caused by headaches, toothaches, arthritis ...
Voltaren
Voltaren (diclofenac) is used to treat pain or inflammation caused by arthritis or ankylosing ...
Diclofenac
Diclofenac is a nonsteroidal anti-inflammatory drug used to treat pain and inflammation associated ...
Naproxen
Naproxen is a nonsteroidal anti-inflammatory drug used to treat pain or inflammation caused by ...
Cyclobenzaprine
Cyclobenzaprine is a muscle relaxant and works by blocking pain sensations. Includes ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.