Ixabepilone and Alcohol/Food Interactions
There is 1 alcohol/food/lifestyle interaction with ixabepilone.
Ixabepilone Food
Moderate Food Interaction
GENERALLY AVOID: Grapefruit juice may increase the plasma concentrations of ixabepilone. The proposed mechanism is inhibition of CYP450 3A4-mediated first-pass metabolism in the gut wall by certain compounds present in grapefruits.
MANAGEMENT: Patients treated with ixabepilone should avoid the consumption of grapefruit or grapefruit juice.
References (1)
- (2007) "Product Information. Ixempra (ixabepilone)." Bristol-Myers Squibb
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Ixabepilone drug interactions
There are 428 drug interactions with ixabepilone.
Ixabepilone disease interactions
There are 4 disease interactions with ixabepilone which include:
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- Drug class: mitotic inhibitors
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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