Ixabepilone Disease Interactions
There are 4 disease interactions with ixabepilone:
Ixabepilone (applies to ixabepilone) cytopenia
Major Potential Hazard, Moderate plausibility. Applicable conditions: Thrombocytopenia, Neutropenia, Immunodeficiency
Ixabepilone is contraindicated in patients who have a neutrophil count <1500 cells/mm3 or a platelet count <100,000 cells/mm3.
Ixabepilone (applies to ixabepilone) liver dysfunction
Major Potential Hazard, Moderate plausibility. Applicable conditions: Liver Disease, Hyperbilirubinemia
The use of ixabepilone in combination with capecitabine is contraindicated in patients with AST or ALT >2.5 x ULN or bilirubin >1 x ULN due to increased risk of toxicity and neutropenia-related death.
Ixabepilone (applies to ixabepilone) cardiovascular
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Arrhythmias, Ischemic Heart Disease, Cardiovascular Disease
The use of ixabepilone in combination with capecitabine may increase cardiac adverse reactions, such as myocardial ischemia and ventricular dysfunction. Care should be exercised when using this agent in combination with capecitabine in patients with a history of cardiac disease. It is recommended to discontinue treatment in patients who develop cardiac ischemia or impaired cardiac function.
Ixabepilone (applies to ixabepilone) neuropathy
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Diabetes Mellitus, Peripheral Neuropathy
The use of ixabepilone in combination with capecitabine may cause peripheral neuropathy. Patients treated with ixabepilone in combination with capecitabine should be monitored for symptoms of neuropathy. Patients experiencing new or worsening symptoms may require a reduction or delay in the dose. Caution should be used when treating patients with diabetes mellitus or preexisting peripheral neuropathy.
Ixabepilone drug interactions
There are 314 drug interactions with ixabepilone
Ixabepilone alcohol/food interactions
There is 1 alcohol/food interaction with ixabepilone
More about ixabepilone
- Side Effects
- During Pregnancy
- Dosage Information
- Drug Interactions
- En Español
- Drug class: mitotic inhibitors
Related treatment guides
Drug Interaction Classification
|No interaction information available.|