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Ixabepilone Pregnancy and Breastfeeding Warnings

Ixabepilone is also known as: Ixempra

Medically reviewed by Drugs.com. Last updated on Aug 5, 2019.

Ixabepilone Pregnancy Warnings

Use should be avoided.

US FDA pregnancy category: D

Comments:
-This drug can harm a developing fetus.
-Adequate methods of contraception should be encouraged.
-If this drug is used during pregnancy, or if the patient becomes pregnant while taking this drug, the patient should be apprised of the potential harm to the fetus.

Animal studies have revealed evidence of ossification of caudal vertebrae, sternebrae and metacarpals, a decrease in implantations and live fetuses, and increased resorptions and embryofetal death. There are no controlled data in human pregnancy.

US FDA pregnancy category D: There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

See references

Ixabepilone Breastfeeding Warnings

A decision should be made to discontinue breastfeeding or discontinue the drug, taking into account the importance of the drug to the mother.

Excreted into human milk: Unknown
Excreted into animal milk: Yes

Comments:
-The effects in the nursing infant are unknown.

See references

References for pregnancy information

  1. "Product Information. Ixempra (ixabepilone)." Bristol-Myers Squibb, Princeton, NJ.

References for breastfeeding information

  1. "Product Information. Ixempra (ixabepilone)." Bristol-Myers Squibb, Princeton, NJ.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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