Fostamatinib and Alcohol/Food Interactions

fostamatinib - hypertension

The use of fostamatinib may cause hypertension. It is recommended to monitor blood pressure every 2 weeks until stable, then monthly and to adjust or initiate antihypertensive therapy to ensure maintenance of blood pressure control during treatment. If increased blood pressure persists despite appropriate therapy, therapy interruption, reduction or discontinuation may be necessary. Caution should be exercised when using this agent in patients with pre-existing hypertension as they may be more susceptible to the hypertensive effects of fostamatinib.