Fostamatinib Side Effects

Medically reviewed by Drugs.com. Last updated on Sep 25, 2022.

Applies to fostamatinib: oral tablet.

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

• severe diarrhea;

• stomach pain (upper right side);

• dark urine, jaundice (yellowing of the skin or eyes);

• headaches, chest pain, shortness of breath; or

• fever, sore throat, or other signs of infection.

Your fostamatinib doses may be delayed or permanently discontinued if you have certain side effects.

Common side effects may include:

• increased blood pressure;

• diarrhea, nausea, stomach pain;

• abnormal liver function tests;

• chest pain;

• dizziness, tiredness;

• rash; or

• cold symptoms such as stuffy nose, sneezing, sore throat.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

For Healthcare Professionals

Applies to fostamatinib: oral tablet.

Hematologic

Common (1% to 10%): Neutropenia^[Ref]

Hepatic

Very common (10% or more): ALT increased (11%)

Common (1% to 10%): AST increased^[Ref]

Respiratory

Very common (10% or more): Respiratory infection (11%)^[Ref]

Other

Common (1% to 10%): Fatigue^[Ref]

Nervous system

Very common (10% or more): Dizziness (11%)^[Ref]

Cardiovascular

Very common (10% or more): Hypertension (28%)^[Ref]

Dermatologic

Common (1% to 10%): Rash (e.g., rash erythematous, rash macular)^[Ref]

Gastrointestinal

Very common (10% or more): Diarrhea (31%), nausea (19%)

Common (1% to 10%): Abdominal pain^[Ref]

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.

Medical Disclaimer