Dexmethylphenidate and Alcohol / Food Interactions
There are 3 alcohol/food/lifestyle interactions with dexmethylphenidate which include:
High Blood Pressure (Hypertension)
Severe Potential Hazard, Moderate plausibility
CNS stimulants - cardiac disease
The use of CNS stimulants is contraindicated in patients with significant cardiovascular impairment such as uncompensated heart failure, severe coronary disease, severe hypertension (including that associated with hyperthyroidism or pheochromocytoma), cardiac structural abnormalities, serious arrhythmias, etc. Sudden death has been reported in adults and children taking CNS stimulant treatment. Additionally, stroke, myocardial infarction, chest pain, syncope, arrhythmias and other symptoms have been reported in adults under treatment. A careful assessment of the cardiovascular status should be done in patients being considered for treatment. This includes family history, physical exam and further cardiac evaluation (EKG and echocardiogram). Patients who develop symptoms should have a detailed cardiac evaluation and if needed, treatment should be suspended.
References
- "Product Information. Dopram (doxapram)." West-Ward Pharmaceutical Corporation, Eatontown, NJ.
High Blood Pressure (Hypertension)
Severe Potential Hazard, Moderate plausibility
CNS stimulants - hypertension
CNS stimulant medications have shown to increase blood pressure and their use is contraindicated in patients with severe hypertension. Caution should be used when administering to patients with preexisting high blood pressure and other cardiovascular conditions. All patients under treatment should be regularly monitored for changes in blood pressure and heart rate.
References
- "Product Information. Dopram (doxapram)." West-Ward Pharmaceutical Corporation, Eatontown, NJ.
High Blood Pressure (Hypertension)
Severe Potential Hazard, High plausibility
methylphenidate - hypertension
Methylphenidate (racemic) and dexmethylphenidate (the more pharmacologically active d-enantiomer) exhibit sympathomimetic activity and may elevate blood pressure and pulse rate. Therapy with these agents should be administered cautiously in patients with hypertension. Blood pressure should be monitored periodically during therapy.
References
- "Product Information. Focalin (dexmethylphenidate)." Mikart Inc, Atlanta, GA.
- "Product Information. Ritalin (methylphenidate)." Novartis Pharmaceuticals, East Hanover, NJ.
dexmethylphenidate drug Interactions
There are 406 drug interactions with dexmethylphenidate
dexmethylphenidate disease Interactions
There are 13 disease interactions with dexmethylphenidate which include:
- Agitation
- Cardiac Disease
- Glaucoma
- Hypertension
- Liver Disease
- Seizure Disorders
- Substance Abuse
- Hypertension
- Seizures Disorders
- Psychiatric Disorders
- Renal Dysfunction
- Tics
- Hematologic Toxicity
See also...
Drug Interaction Classification
The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
| Major | Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. |
| Moderate | Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. |
| Minor | Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. |
Do not stop taking any medications without consulting your healthcare provider.
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