Desvenlafaxine and Alcohol/Food Interactions
There are 2 alcohol/food/lifestyle interactions with desvenlafaxine.
Moderate Food Interaction
Alcohol can increase the nervous system side effects of desvenlafaxine such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with desvenlafaxine. Do not use more than the recommended dose of desvenlafaxine, and avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medication affects you. Talk to your doctor or pharmacist if you have any questions or concerns.
High Blood Pressure (Hypertension)
Moderate Potential Hazard, Moderate plausibility
SNRI antidepressants - hypertension
Selective serotonin and norepinephrine reuptake inhibitor antidepressants (SNRIs) have been associated with sustained increases in blood pressure. Therapy with SNRI antidepressants should be administered cautiously in patients with preexisting hypertension. Blood pressure should be assessed prior to initiating treatment and monitored regularly. The dose should be reduced or discontinued if necessary.
- "Product Information. Effexor (venlafaxine)." Wyeth-Ayerst Laboratories (2001):
- "Product Information. Cymbalta (duloxetine)." Lilly, Eli and Company (2004):
- "Product Information. Pristiq (desvenlafaxine)." Wyeth Laboratories (2008):
- "Product Information. Savella (milnacipran)." Forest Pharmaceuticals (2009):
- "Product Information. Fetzima (levomilnacipran)." Forest Pharmaceuticals (2013):
Desvenlafaxine drug interactions
There are 461 drug interactions with desvenlafaxine.
Desvenlafaxine disease interactions
There are 8 disease interactions with desvenlafaxine which include:
- renal disease
- urinary tract obstruction
More about desvenlafaxine
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- Drug class: serotonin-norepinephrine reuptake inhibitors
Related treatment guides
Drug Interaction Classification
|Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.|
|Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.|
|Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.|
|No interaction information available.|
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