Darolutamide and Alcohol/Food Interactions
There is 1 alcohol/food/lifestyle interaction with darolutamide.
Moderate
Darolutamide Food/Lifestyle
Moderate Food Interaction
ADJUST DOSING INTERVAL: Food enhances the oral absorption of darolutamide. According to the prescribing information, bioavailability of darolutamide increased by 2.0 to 2.5-fold when administered with food. A similar increase in exposure was observed for the active metabolite keto-darolutamide.
MANAGEMENT: Darolutamide should be administered with food.
References (1)
- (2019) "Product Information. Nubeqa (darolutamide)." Bayer HealthCare Pharmaceuticals Inc.
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Darolutamide drug interactions
There are 313 drug interactions with darolutamide.
Darolutamide disease interactions
There are 2 disease interactions with darolutamide which include:
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- Drug class: antiandrogens
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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