Colesevelam and Alcohol/Food Interactions
There is 1 alcohol/food/lifestyle interaction with colesevelam.
Multivitamins With Minerals Colesevelam
Moderate Drug Interaction
Consumer information for this interaction is not currently available.
ADJUST DOSING INTERVAL: Bile acid sequestrants can decrease the absorption of fat-soluble vitamins A, D, E, and K. By binding bile acids, these agents may interfere with normal fat digestion and absorption, thereby preventing the absorption of fat-soluble vitamins. Colesevelam did not induce any clinically significant reduction in the absorption of vitamins A, D, E or K during clinical studies of up to one year. However, chronic use of other bile acid sequestrants has been rarely associated with an increased bleeding tendency due to hypoprothrombinemia resulting from vitamin K deficiency. Isolated cases of Vitamin A (including one case of night blindness) and D deficiencies have also been reported with chronic cholestyramine therapy.
MANAGEMENT: Oral vitamin supplements should be administered at least 4 hours before colesevelam to minimize the potential impact on their absorption.
Colesevelam drug interactions
There are 91 drug interactions with colesevelam.
Colesevelam disease interactions
There are 4 disease interactions with colesevelam which include:
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Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
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