Actonel with Calcium and Alcohol/Food Interactions
There are 4 alcohol/food/lifestyle interactions with Actonel with Calcium (calcium carbonate / risedronate).
Calcium Carbonate Multivitamins With Minerals
Moderate Drug Interaction
Risedronate and calcium carbonate should not be taken orally at the same time. Products that contain magnesium, aluminum, calcium, iron, and/or other minerals may interfere with the absorption of risedronate into the bloodstream and reduce its effectiveness. You should take calcium carbonate at least 30 minutes after the risedronate dose. Talk to a healthcare professional if you are not sure whether a product contains something that could potentially interact with your medication or if you have questions on how to take this or other medications you are prescribed. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Multivitamins With Minerals Risedronate
Moderate Drug Interaction
Risedronate and multivitamin with minerals should not be taken orally at the same time. Products that contain magnesium, aluminum, calcium, iron, and/or other minerals may interfere with the absorption of risedronate into the bloodstream and reduce its effectiveness. You should take multivitamin with minerals at least 30 minutes after the risedronate dose. Talk to a healthcare professional if you are not sure whether a product contains something that could potentially interact with your medication or if you have questions on how to take this or other medications you are prescribed. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Calcium Carbonate Food
Moderate Food Interaction
Consumer information for this interaction is not currently available.
ADJUST DOSING INTERVAL: Administration with food may increase the absorption of calcium. However, foods high in oxalic acid (spinach or rhubarb), or phytic acid (bran and whole grains) may decrease calcium absorption.
MANAGEMENT: Calcium may be administered with food to increase absorption. Consider withholding calcium administration for at least 2 hours before or after consuming foods high in oxalic acid or phytic acid.
Risedronate Food
Moderate Food Interaction
Consumer information for this interaction is not currently available.
ADJUST DOSING INTERVAL: Food significantly decreases the bioavailability of risedronate, possibly to negligible levels.
MANAGEMENT: Risedronate should be administered with 180 to 240 mL (6 to 8 ounces) of plain water, at least 30 minutes before the first food, beverage, or medication of the day. Patients should remain upright for at least 30 minutes following administration of risedronate.
Switch to professional interaction data
Actonel with Calcium drug interactions
There are 309 drug interactions with Actonel with Calcium (calcium carbonate / risedronate).
Actonel with Calcium disease interactions
There are 10 disease interactions with Actonel with Calcium (calcium carbonate / risedronate) which include:
- ONJ
- hypocalcemia
- upper GI mucosal irritation
- phosphate calcifications
- cardiac contraction/conduction
- malabsorption
- renal dysfunction
- sarcoidosis
- asthma
- renal dysfunction
More about Actonel with Calcium (calcium carbonate / risedronate)
- Actonel with Calcium consumer information
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- Dosage information
- During pregnancy
- FDA approval history
- Drug class: bisphosphonates
Related treatment guides
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.