Aspirin/diphenhydramine and Alcohol/Food Interactions
There are 3 alcohol/food/lifestyle interactions with aspirin / diphenhydramine.
Aspirin Caffeine
Minor Drug Interaction
Information for this minor interaction is available on the professional version.
Aspirin Alcohol (Ethanol)
Moderate Drug Interaction
Ask your doctor before using aspirin together with ethanol (alcohol). Do not drink alcohol while taking aspirin. Alcohol can increase your risk of stomach bleeding caused by aspirin. Call your doctor at once if you have symptoms of bleeding in your stomach or intestines. This includes black, bloody, or tarry stools, or coughing up blood or vomit that looks like coffee grounds. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Diphenhydramine Alcohol (Ethanol)
Moderate Drug Interaction
Ask your doctor before using diphenhydrAMINE together with ethanol (alcohol). Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are taking diphenhydrAMINE. You should be warned not to exceed recommended dosages and to avoid activities requiring mental alertness. If your doctor prescribes these medications together, you may need a dose adjustment to safely take this combination. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Switch to professional interaction data
Aspirin/diphenhydramine drug interactions
There are 718 drug interactions with aspirin / diphenhydramine.
Aspirin/diphenhydramine disease interactions
There are 17 disease interactions with aspirin / diphenhydramine which include:
- depression
- coagulation
- asthma
- GI toxicity
- renal dysfunction
- Reye's syndrome
- anticholinergic effects
- asthma/COPD
- cardiovascular
- renal/liver disease
- glaucoma
- liver disease
- resp depression
- anemia
- dialysis
- G-6-PD deficiency
- hepatotoxicity
More about aspirin / diphenhydramine
- Check interactions
- Compare alternatives
- Side effects
- Dosage information
- During pregnancy
- Drug class: analgesic combinations
Related treatment guides
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.