Aspirin/diphenhydramine Interactions
There are 721 drugs known to interact with aspirin/diphenhydramine, along with 17 disease interactions, and 2 alcohol/food interactions. Of the total drug interactions, 76 are major, 624 are moderate, and 21 are minor.
- View all 721 medications that may interact with aspirin/diphenhydramine
- View aspirin/diphenhydramine alcohol/food interactions (2)
- View aspirin/diphenhydramine disease interactions (17)
Most frequently checked interactions
View interaction reports for aspirin / diphenhydramine and the medicines listed below.
- Arthritis Pain Formula (aluminum hydroxide / aspirin / calcium carbonate / magnesium hydroxide)
- Arthritis Pain Formula (aluminum hydroxide / aspirin / calcium carbonate / magnesium hydroxide)
- Centrum Silver (multivitamin with minerals)
- Centrum Silver (multivitamin with minerals)
- Coreg (carvedilol)
- Coreg (carvedilol)
- Crestor (rosuvastatin)
- Crestor (rosuvastatin)
- Cymbalta (duloxetine)
- Cymbalta (duloxetine)
- Entresto (sacubitril / valsartan)
- Entresto (sacubitril / valsartan)
- Gemtesa (vibegron)
- Gemtesa (vibegron)
- Lasix (furosemide)
- Lasix (furosemide)
- Lortab (acetaminophen / hydrocodone)
- Lortab (acetaminophen / hydrocodone)
- Lyrica (pregabalin)
- Lyrica (pregabalin)
- Metoprolol Tartrate (metoprolol)
- Metoprolol Tartrate (metoprolol)
- Xanax (alprazolam)
- Xanax (alprazolam)
Aspirin/diphenhydramine alcohol/food interactions
There are 2 alcohol/food interactions with aspirin / diphenhydramine.
Aspirin/diphenhydramine disease interactions
There are 17 disease interactions with aspirin / diphenhydramine which include:
- depression
- coagulation
- asthma
- GI toxicity
- renal dysfunction
- Reye's syndrome
- anticholinergic effects
- asthma/COPD
- cardiovascular
- renal/liver disease
- glaucoma
- liver disease
- resp depression
- anemia
- dialysis
- G-6-PD deficiency
- hepatotoxicity
Report options
More about aspirin / diphenhydramine
- Compare alternatives
- Side effects
- Dosage information
- During pregnancy
- Drug class: analgesic combinations
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Diclofenac
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Naproxen
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Amitriptyline
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Hydroxyzine
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Tramadol
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Cyclobenzaprine
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.