Aspirin Lite Coat and Alcohol/Food Interactions
There are 2 alcohol/food/lifestyle interactions with Aspirin Lite Coat (aspirin).
Aspirin Caffeine
Minor Drug Interaction
One study has reported that coadministration of caffeine and aspirin lead to a 25% increase in the rate of appearance and 17% increase in maximum concentration of salicylate in the plasma. A significantly higher area under the plasma concentration time curve of salicylate was also reported when both drugs were administered together. The exact mechanism of this interaction has not been specified. Physicians and patients should be aware that coadministration of aspirin and caffeine may lead to higher salicylate levels faster.
References (1)
- Yoovathaworn KC, Sriwatanakul K, Thithapandha A (1986) "Influence of caffeine on aspirin pharmacokinetics." Eur J Drug Metab Pharmacokinet, 11, p. 71-6
Aspirin Alcohol (Ethanol)
Moderate Drug Interaction
GENERALLY AVOID: The concurrent use of aspirin or nonsteroidal anti-inflammatory drugs (NSAIDs) and ethanol may lead to gastrointestinal (GI) blood loss. The mechanism may be due to a combined local effect as well as inhibition of prostaglandins leading to decreased integrity of the GI lining.
MANAGEMENT: Patients should be counseled on this potential interaction and advised to refrain from alcohol consumption while taking aspirin or NSAIDs.
References (1)
- (2002) "Product Information. Motrin (ibuprofen)." Pharmacia and Upjohn
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Aspirin Lite Coat drug interactions
There are 371 drug interactions with Aspirin Lite Coat (aspirin).
Aspirin Lite Coat disease interactions
There are 9 disease interactions with Aspirin Lite Coat (aspirin) which include:
- coagulation
- asthma
- GI toxicity
- renal dysfunction
- Reye's syndrome
- anemia
- dialysis
- G-6-PD deficiency
- hepatotoxicity
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More about Aspirin Lite Coat (aspirin)
- Check interactions
- Compare alternatives
- Latest FDA alerts (3)
- Side effects
- Dosage information
- During pregnancy
- Drug class: platelet aggregation inhibitors
- Breastfeeding
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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