Excedrin PM and Alcohol/Food Interactions
There are 2 alcohol/food/lifestyle interactions with Excedrin PM (acetaminophen / diphenhydramine).
acetaminophen Alcohol (Ethanol)
Major Drug Interaction
Ask your doctor before using acetaminophen together with ethanol. This can cause serious side effects that affect your liver. Call your doctor immediately if you experience a fever, chills, joint pain or swelling, excessive tiredness or weakness, unusual bleeding or bruising, skin rash or itching, loss of appetite, nausea, vomiting, or yellowing of the skin or the whites of your eyes. If your doctor does prescribe these medications together, you may need a dose adjustment or special tests to safely take both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
diphenhydrAMINE Alcohol (Ethanol)
Moderate Drug Interaction
Ask your doctor before using diphenhydrAMINE together with ethanol. Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are taking diphenhydrAMINE. You should be warned not to exceed recommended dosages and to avoid activities requiring mental alertness. If your doctor prescribes these medications together, you may need a dose adjustment to safely take this combination. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Excedrin PM drug interactions
There are 476 drug interactions with Excedrin PM (acetaminophen / diphenhydramine).
Excedrin PM disease interactions
There are 11 disease interactions with Excedrin PM (acetaminophen / diphenhydramine) which include:
- liver disease
- anticholinergic effects
- renal/liver disease
- liver disease
- resp depression
More about Excedrin PM (acetaminophen / diphenhydramine)
- Check interactions
- Reviews (7)
- Drug images
- Side effects
- Dosage information
- During pregnancy
- Drug class: analgesic combinations
Related treatment guides
Drug Interaction Classification
|Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.|
|Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.|
|Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.|
|No interaction information available.|
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.