Effexor XR Drug Interactions
Currently displaying a list of 702 drugs known to interact with Effexor XR (venlafaxine).
- 152 major drug interactions
- 546 moderate drug interactions
- 4 minor drug interactions
Medications known to interact with Effexor XR
Note: Showing generic names only.
5
A
- abametapir topical
- abarelix
- abciximab
- abrocitinib
- acalabrutinib
- acetazolamide
- acetylcarbromal
- acrivastine
- adagrasib
- adenosine
- ado-trastuzumab emtansine
- albuterol
- aldesleukin
- alfentanil
- alfuzosin
- allopurinol
- almotriptan
- alprazolam
- alteplase
- amifampridine
- amiloride
- amiodarone
- amisulpride
- amitriptyline
- amobarbital
- amoxapine
- amphetamine
- amprenavir
- anagrelide
- anisindione
- anistreplase
- antithrombin (recombinant)
- antithrombin iii
- apalutamide
- apixaban
- apomorphine
- apraclonidine ophthalmic
- aprepitant
- ardeparin
- arformoterol
- argatroban
- aripiprazole
- arsenic trioxide
- asciminib
- asenapine
- aspirin
- astemizole
- atazanavir
- atomoxetine
- avacopan
- avapritinib
- azatadine
- azithromycin
B
- baclofen
- bedaquiline
- belzutifan
- bendroflumethiazide
- benzgalantamine
- benzphetamine
- benzthiazide
- benztropine
- bepridil
- berotralstat
- betrixaban
- bicalutamide
- biperiden
- bisacodyl
- bismuth subsalicylate
- bitolterol
- bivalirudin
- boceprevir
- brexanolone
- brexpiprazole
- brimonidine ophthalmic
- brimonidine topical
- brivaracetam
- bromfenac
- bromocriptine
- brompheniramine
- bumetanide
- buprenorphine
- bupropion
- buspirone
- butabarbital
- butalbital
- butorphanol
C
- cabozantinib
- cangrelor
- cannabidiol
- cannabis
- capivasertib
- caplacizumab
- carbamazepine
- carbetapentane
- carbinoxamine
- cariprazine
- carisoprodol
- casanthranol
- cascara sagrada
- castor oil
- celecoxib
- cenobamate
- ceritinib
- cetirizine
- chlophedianol
- chloral hydrate
- chloramphenicol
- chlordiazepoxide
- chlormezanone
- chloroquine
- chlorothiazide
- chlorphenesin
- chlorpheniramine
- chlorpromazine
- chlorthalidone
- chlorzoxazone
- choline salicylate
- cilostazol
- cimetidine
- cinacalcet
- ciprofloxacin
- cisapride
- citalopram
- clarithromycin
- clemastine
- clobazam
- clofazimine
- clomipramine
- clonazepam
- clonidine
- clopidogrel
- clorazepate
- clotrimazole
- clozapine
- cobicistat
- codeine
- conivaptan
- crizotinib
- cyclizine
- cyclobenzaprine
- cyclosporine
- cyproheptadine
D
- dabigatran
- dalteparin
- danaparoid
- danazol
- dantrolene
- daridorexant
- darolutamide
- darunavir
- dasatinib
- daunorubicin
- daunorubicin liposomal
- deferasirox
- defibrotide
- degarelix
- delavirdine
- desipramine
- desirudin
- desmopressin
- desvenlafaxine
- deutetrabenazine
- dexbrompheniramine
- dexfenfluramine
- dexmedetomidine
- dextroamphetamine
- dextromethorphan
- dezocine
- diazepam
- dichlorphenamide
- diclofenac
- dicumarol
- diethylpropion
- difelikefalin
- diflunisal
- dihydroergotamine
- diltiazem
- dimenhydrinate
- diphenhydramine
- dipivefrin ophthalmic
- dipyridamole
- disopyramide
- divalproex sodium
- dobutamine
- dofetilide
- dolasetron
- donepezil
- dopamine
- doxepin
- doxepin topical
- doxorubicin
- doxorubicin liposomal
- doxylamine
- dronabinol
- dronedarone
- droperidol
- drotrecogin alfa
- duloxetine
- duvelisib
E
- echinacea
- edoxaban
- efavirenz
- eletriptan
- encorafenib
- enoxaparin
- entacapone
- entrectinib
- enzalutamide
- ephedrine
- ephedrine nasal
- epinephrine
- epinephrine ophthalmic
- epinephrine topical
- epirubicin
- eplerenone
- epoprostenol
- eptifibatide
- ergotamine
- eribulin
- erythromycin
- escitalopram
- eslicarbazepine
- estazolam
- eszopiclone
- ethacrynic acid
- ethanol
- ethosuximide
- ethotoin
- etodolac
- etrasimod
- evening primrose
- ezogabine
F
- famotidine
- fedratinib
- felbamate
- fenfluramine
- fenoprofen
- fentanyl
- fexinidazole
- fingolimod
- flavoxate
- flecainide
- flibanserin
- fluconazole
- fluoxetine
- fluphenazine
- flurazepam
- flurbiprofen
- flutamide
- fluvoxamine
- fondaparinux
- formoterol
- fosamprenavir
- fosaprepitant
- foscarnet
- fosphenytoin
- fostamatinib
- fostemsavir
- frovatriptan
- furazolidone
- furosemide
G
- gabapentin
- gabapentin enacarbil
- galantamine
- ganaxolone
- gatifloxacin
- gemifloxacin
- gepirone
- gilteritinib
- ginkgo
- givinostat
- glasdegib
- glofitamab
- glycerin
- glycerol phenylbutyrate
- goldenseal
- goserelin
- granisetron
- grepafloxacin
H
- halazepam
- halofantrine
- haloperidol
- halothane
- heparin
- heroin
- histrelin
- hydrochlorothiazide
- hydrocodone
- hydroflumethiazide
- hydromorphone
- hydroxyamphetamine ophthalmic
- hydroxychloroquine
- hydroxyzine
I
- ibritumomab
- ibrutinib
- ibuprofen
- ibutilide
- idarubicin
- idelalisib
- ifosfamide
- iloperidone
- iloprost
- imatinib
- imipramine
- indacaterol
- indapamide
- indinavir
- indomethacin
- inotersen
- inotuzumab ozogamicin
- iobenguane I 123
- iobenguane I 131
- iodine i 131 tositumomab
- ioflupane I 123
- iohexol
- iomeprol
- iopamidol
- isavuconazonium
- isocarboxazid
- isoetharine
- isoniazid
- isoproterenol
- itraconazole
- ivabradine
- ivacaftor
- ivosidenib
K
L
- lacosamide
- lactitol
- lactulose
- lamotrigine
- lapatinib
- larotrectinib
- lasmiditan
- lazertinib
- lefamulin
- lemborexant
- lenacapavir
- lenvatinib
- lepirudin
- letermovir
- leuprolide
- levalbuterol
- levetiracetam
- levmetamfetamine nasal
- levocetirizine
- levodopa
- levofloxacin
- levoketoconazole
- levomethadyl acetate
- levomilnacipran
- levorphanol
- lidocaine
- lindane topical
- linezolid
- lisdexamfetamine
- lithium
- lofexidine
- lomefloxacin
- lomitapide
- lonafarnib
- lonapegsomatropin
- loperamide
- lorazepam
- lorcaserin
- lorlatinib
- loxapine
- lumateperone
- lurasidone
M
- ma huang
- macimorelin
- magnesium citrate
- magnesium hydroxide
- magnesium salicylate
- mannitol
- maprotiline
- mavorixafor
- mazindol
- meclofenamate
- mefenamic acid
- mefloquine
- melatonin
- meloxicam
- meperidine
- mephentermine
- mephenytoin
- mephobarbital
- meprobamate
- mesoridazine
- metaproterenol
- metaraminol
- metaxalone
- methadone
- methamphetamine
- methazolamide
- methocarbamol
- methohexital
- methotrimeprazine
- methoxamine
- methsuximide
- methyclothiazide
- methylene blue
- methysergide maleate
- metoclopramide
- metolazone
- metrizamide
- metronidazole
- metyrosine
- mibefradil
- miconazole
- midazolam
- midodrine
- midostaurin
- mifepristone
- milnacipran
- mineral oil
- mirtazapine
- mitotane
- mobocertinib
- molindone
- morphine
- morphine liposomal
- moxifloxacin
N
- nabilone
- nabumetone
- nalbuphine
- naphazoline nasal
- naphazoline ophthalmic
- naproxen
- naratriptan
- nefazodone
- nelfinavir
- nevirapine
- nifedipine
- nilotinib
- nilutamide
- norepinephrine
- norfloxacin
- nortriptyline
O
- ofloxacin
- olanzapine
- oliceridine
- olodaterol
- olopatadine nasal
- olutasidenib
- omaveloxolone
- ondansetron
- opicapone
- opium
- orphenadrine
- osilodrostat
- osimertinib
- oxaliplatin
- oxaprozin
- oxazepam
- oxcarbazepine
- oxycodone
- oxymetazoline nasal
- oxymetazoline ophthalmic
- oxymetazoline topical
- oxymorphone
- oxytocin
- ozanimod
P
- pacritinib
- palbociclib
- paliperidone
- palonosetron
- panobinostat
- papaverine
- paraldehyde
- paramethadione
- paroxetine
- pasireotide
- pazopanib
- pentamidine
- pentazocine
- pentobarbital
- perampanel
- perflutren
- pergolide
- perphenazine
- pexidartinib
- phenacemide
- phendimetrazine
- phenelzine
- phenobarbital
- phenolphthalein
- phensuximide
- phentermine
- phenylbutazone
- phenylephrine
- phenylephrine nasal
- phenylephrine ophthalmic
- phenylephrine topical
- phenylpropanolamine
- phenytoin
- pimavanserin
- pimozide
- pirbuterol
- piroxicam
- pirtobrutinib
- pitolisant
- plasminogen, human
- plicamycin
- polyethylene glycol 3350
- polyethylene glycol 3350 with electrolytes
- polythiazide
- ponatinib
- ponesimod
- porfimer
- posaconazole
- pralsetinib
- pramipexole
- prasugrel
- pregabalin
- primaquine
- primidone
- probucol
- procainamide
- procarbazine
- prochlorperazine
- procyclidine
- promazine
- promethazine
- propafenone
- propiomazine
- propofol
- propoxyphene
- propylhexedrine nasal
- protein c
- protriptyline
- pseudoephedrine
- pyrilamine
Q
R
- racepinephrine
- ramelteon
- ramucirumab
- ranolazine
- rasagiline
- regorafenib
- relugolix
- remdesivir
- remifentanil
- remimazolam
- repotrectinib
- reteplase
- revumenib
- ribociclib
- rilpivirine
- risperidone
- ritlecitinib
- ritodrine
- ritonavir
- rivaroxaban
- rivastigmine
- rizatriptan
- romidepsin
- ropinirole
- rotigotine
- rucaparib
- rufinamide
- ruxolitinib
S
- safinamide
- salmeterol
- salsalate
- saquinavir
- scopolamine
- secobarbital
- selegiline
- selpercatinib
- senna
- sertraline
- sevoflurane
- sibutramine
- siponimod
- sodium oxybate
- sodium salicylate
- sodium thiosalicylate
- solifenacin
- solriamfetol
- somapacitan-beco
- somatrem
- somatrogon
- somatropin
- sorafenib
- sotalol
- sparfloxacin
- spironolactone
- st. john's wort
- stiripentol
- streptokinase
- sufentanil
- sulfamethoxazole
- sulfinpyrazone
- sulindac
- sumatriptan
- sunitinib
- suvorexant
T
- tacrine
- tacrolimus
- tamoxifen
- tapentadol
- tasimelteon
- tazemetostat
- tebentafusp
- tedizolid
- telaprevir
- telavancin
- telithromycin
- telotristat
- temazepam
- tenecteplase
- terbinafine
- terbutaline
- terfenadine
- tetrabenazine
- tetrahydrozoline nasal
- tetrahydrozoline ophthalmic
- thalidomide
- thioridazine
- thiothixene
- tiagabine
- ticagrelor
- ticlopidine
- tinzaparin
- tirofiban
- tirzepatide
- tizanidine
- tolcapone
- tolmetin
- tolterodine
- topiramate
- toremifene
- torsemide
- tositumomab
- tovorafenib
- tramadol
- tranylcypromine
- trazodone
- treosulfan
- treprostinil
- triamterene
- triazolam
- trichlormethiazide
- triclabendazole
- trifluoperazine
- triflupromazine
- trihexyphenidyl
- trimeprazine
- trimethadione
- trimethobenzamide
- trimipramine
- tripelennamine
- triprolidine
- triptorelin
- trofinetide
- troglitazone
- troleandomycin
- tryptophan
- tucatinib
- turmeric
U
V
- vadadustat
- valbenazine
- valerian
- valproic acid
- vandetanib
- vardenafil
- vasopressin
- vemurafenib
- verapamil
- vigabatrin
- vilazodone
- viloxazine
- voclosporin
- vonoprazan
- vorapaxar
- vorasidenib
- voriconazole
- vortioxetine
- voxelotor
W
X
Y
Z
Effexor XR alcohol/food interactions
There are 2 alcohol/food interactions with Effexor XR (venlafaxine).
Effexor XR disease interactions
There are 11 disease interactions with Effexor XR (venlafaxine) which include:
- depression
- renal disease
- renal/liver disease
- mania
- glaucoma
- hypertension
- hyponatremia
- mania
- seizures
- urinary tract obstruction
- weight loss
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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