Trazodone Interactions
There are 675 drugs known to interact with trazodone, along with 8 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 138 are major, 522 are moderate, and 15 are minor.
- View all 675 medications that may interact with trazodone
- View trazodone alcohol/food interactions (1)
- View trazodone disease interactions (8)
Most frequently checked interactions
View interaction reports for trazodone and the medicines listed below.
- Abilify (aripiprazole)
- Adderall (amphetamine / dextroamphetamine)
- Ambien (zolpidem)
- Ativan (lorazepam)
- Benadryl (diphenhydramine)
- Cymbalta (duloxetine)
- Fish Oil (omega-3 polyunsaturated fatty acids)
- Flexeril (cyclobenzaprine)
- Flonase (fluticasone nasal)
- Klonopin (clonazepam)
- Lamictal (lamotrigine)
- Lexapro (escitalopram)
- Lyrica (pregabalin)
- Metoprolol Succinate ER (metoprolol)
- Norco (acetaminophen / hydrocodone)
- Prozac (fluoxetine)
- Seroquel (quetiapine)
- Singulair (montelukast)
- Synthroid (levothyroxine)
- Topamax (topiramate)
- Tylenol (acetaminophen)
- Vitamin B12 (cyanocobalamin)
- Vitamin C (ascorbic acid)
- Vitamin D3 (cholecalciferol)
- Vyvanse (lisdexamfetamine)
- Wellbutrin (bupropion)
- Wellbutrin XL (bupropion)
- Xanax (alprazolam)
- Zoloft (sertraline)
- Zyrtec (cetirizine)
Trazodone alcohol/food interactions
There is 1 alcohol/food interaction with trazodone.
Trazodone disease interactions
There are 8 disease interactions with trazodone which include:
- angle closure glaucoma
- mania
- seizures
- suicidality
- cardiovascular disease
- hyponatremia
- hypotension
- renal/liver disease
Report options
More about trazodone
- trazodone consumer information
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- Reviews (1,439)
- Drug images
- Latest FDA alerts (2)
- Side effects
- Dosage information
- Patient tips
- During pregnancy
- Support group
- Drug class: phenylpiperazine antidepressants
- Breastfeeding
- En español
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Lexapro
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Vraylar
Vraylar is a once a day antipsychotic medication used to treat mental health or mood disorders ...
Zoloft
Zoloft is an antidepressant used to treat major depression, obsessive-compulsive disorder, panic ...
Seroquel
Seroquel is used to treat the symptoms of schizophrenia, bipolar disorder and major depressive ...
Prozac
Prozac (fluoxetine) is an SSRI antidepressant used to treat depression, OCD, panic disorder ...
Cymbalta
Cymbalta (duloxetine) is used to treat major depressive disorder, general anxiety disorder and ...
Wellbutrin
Wellbutrin (bupropion) is used to treat major depressive disorder and seasonal affective disorder ...
Celexa
Celexa (citalopram) is an antidepressant in a group of drugs called selective serotonin reuptake ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
