Ultram ER Interactions
There are 712 drugs known to interact with Ultram ER (tramadol), along with 12 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 318 are major, 391 are moderate, and 3 are minor.
- View all 712 medications that may interact with Ultram ER
- View Ultram ER alcohol/food interactions (1)
- View Ultram ER disease interactions (12)
Most frequently checked interactions
View interaction reports for Ultram ER (tramadol) and the medicines listed below.
- amitriptyline
- atenolol
- Celebrex (celecoxib)
- clonazepam
- cyclobenzaprine
- Cymbalta (duloxetine)
- Flexeril (cyclobenzaprine)
- gabapentin
- hydrochlorothiazide
- levothyroxine
- Lexapro (escitalopram)
- Lidoderm (lidocaine topical)
- Lipitor (atorvastatin)
- lisinopril
- Lyrica (pregabalin)
- metformin
- Neurontin (gabapentin)
- Nexium (esomeprazole)
- Norco (acetaminophen / hydrocodone)
- omeprazole
- oxycodone
- prednisone
- Singulair (montelukast)
- Synthroid (levothyroxine)
- Topamax (topiramate)
- trazodone
- Vitamin B12 (cyanocobalamin)
- Vitamin D3 (cholecalciferol)
- Xanax (alprazolam)
- Zanaflex (tizanidine)
Ultram ER alcohol/food interactions
There is 1 alcohol/food interaction with Ultram ER (tramadol).
Ultram ER disease interactions
There are 12 disease interactions with Ultram ER (tramadol) which include:
- gastrointestinal obstruction
- acute alcohol intoxication
- drug dependence
- respiratory depression
- gastrointestinal conditions
- hypoglycemia
- hypotension
- intracranial pressure
- liver disease
- renal dysfunction
- seizure disorders
- suicidal
More about Ultram ER (tramadol)
- Ultram ER consumer information
- Compare alternatives
- Reviews (34)
- Drug images
- Latest FDA alerts (4)
- Side effects
- Dosage information
- During pregnancy
- Drug class: Opioids (narcotic analgesics)
- Breastfeeding
Related treatment guides
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
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Naproxen
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Oxycodone
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Hydroxyzine
Hydroxyzine is an antihistamine used to treat itching, hives, and anxiety. It also acts as a ...
Paracetamol
Paracetamol (Panadol, Calpol, Alvedon) is a widely used over-the-counter painkiller and fever ...
Cyclobenzaprine
Cyclobenzaprine is a muscle relaxant and works by blocking pain sensations. Includes ...
Duloxetine
Duloxetine is a selective serotonin and norepinephrine reuptake inhibitor antidepressant used to ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.