Yondelis Drug Interactions
Currently displaying a list of 665 drugs known to interact with Yondelis (trabectedin).
- 89 major drug interactions
- 576 moderate drug interactions
Medications known to interact with Yondelis
Note: Showing generic names only.
A
- abacavir
- abametapir topical
- abemaciclib
- abiraterone
- abrocitinib
- acarbose
- acetaminophen
- acitretin
- adagrasib
- adalimumab
- adenovirus vaccine
- ado-trastuzumab emtansine
- afatinib
- aldesleukin
- alectinib
- alefacept
- alemtuzumab
- allopurinol
- ambrisentan
- aminoglutethimide
- aminosalicylic acid
- amiodarone
- amobarbital
- amprenavir
- anakinra
- anthrax vaccine adsorbed
- apalutamide
- aprepitant
- aprocitentan
- armodafinil
- asciminib
- ashwaganda
- asparaginase erwinia chrysanthemi
- asparaginase escherichia coli
- atazanavir
- atezolizumab
- atomoxetine
- atorvastatin
- atovaquone
- atrasentan
- auranofin
- aurothioglucose
- avacopan
- avelumab
- axicabtagene ciloleucel
- axitinib
- azathioprine
- azithromycin
B
- baricitinib
- bcg
- bcg vaccine
- bedaquiline
- belinostat
- belumosudil
- belzutifan
- benazepril
- bendamustine
- benznidazole
- berotralstat
- bexarotene
- bicalutamide
- bifidobacterium infantis
- bifidobacterium longum
- binimetinib
- black cohosh
- bleomycin
- blinatumomab
- boceprevir
- bortezomib
- bosentan
- bosutinib
- brentuximab
- brewer's yeast
- brexucabtagene autoleucel
- bromfenac
- bupropion
- busulfan
- butabarbital
- butalbital
C
- cabazitaxel
- calaspargase pegol
- canakinumab
- candida albicans extract
- cannabidiol
- capecitabine
- capivasertib
- capmatinib
- captopril
- carbamazepine
- carboplatin
- carfilzomib
- carmustine
- caspofungin
- celecoxib
- cemiplimab
- cenobamate
- ceritinib
- cerivastatin
- certolizumab
- chaparral
- chenodiol
- chikungunya vaccine, live (cvx 317)
- chikungunya vaccine, recombinant (cvx 329)
- chlorambucil
- chloramphenicol
- chloramphenicol ophthalmic
- chloramphenicol otic
- chloroquine
- chlorzoxazone
- cholera vaccine
- cholera vaccine, live
- ciltacabtagene autoleucel
- cimetidine
- ciprofloxacin
- cisplatin
- cladribine
- clarithromycin
- clavulanate
- clofarabine
- clofibrate
- clotrimazole
- clozapine
- cobicistat
- cobimetinib
- coccidioidin skin test
- colchicine
- comfrey
- conivaptan
- cosibelimab
- COVID-19 mRNA (Moderna) vaccine
- COVID-19 mRNA (Pfizer) vaccine
- crizotinib
- cyclophosphamide
- cyclosporine
- cytarabine
- cytarabine liposomal
D
- dabrafenib
- dacarbazine
- daclizumab
- dactinomycin
- danazol
- danicopan
- dantrolene
- dapsone
- daridorexant
- darunavir
- dasatinib
- daunorubicin
- daunorubicin liposomal
- decitabine
- deferasirox
- deferiprone
- dehydroepiandrosterone
- delandistrogene moxeparvovec
- delavirdine
- dengue vaccine
- denosumab
- deucravacitinib
- dexamethasone
- diclofenac
- diclofenac topical
- didanosine
- diltiazem
- dimethyl fumarate
- dinutuximab
- diroximel fumarate
- disulfiram
- divalproex sodium
- docetaxel
- dolutegravir
- dostarlimab
- doxorubicin
- doxorubicin liposomal
- dronedarone
- duloxetine
- durvalumab
- duvelisib
E
- echinacea
- efalizumab
- efavirenz
- efbemalenograstim alfa
- eflapegrastim
- eflornithine
- elafibranor
- elagolix
- elotuzumab
- elranatamab
- eltrombopag
- emtricitabine
- enalapril
- enalaprilat
- encorafenib
- enfortumab vedotin
- ensartinib
- entrectinib
- enzalutamide
- epirubicin
- eribulin
- erlotinib
- erythromycin
- eslicarbazepine
- etanercept
- ethambutol
- ethanol
- ethionamide
- ethotoin
- etodolac
- etoposide
- etranacogene dezaparvovec
- etrasimod
- etravirine
- etretinate
F
- febuxostat
- fedratinib
- felbamate
- fenfluramine
- fenofibrate
- fenofibric acid
- fenoprofen
- fexinidazole
- fezolinetant
- fidanacogene elaparvovec
- filgrastim
- fingolimod
- fitusiran
- floxuridine
- fluconazole
- fludarabine
- fluorouracil
- fluoxymesterone
- flurbiprofen
- flutamide
- fluvastatin
- fluvoxamine
- fosamprenavir
- fosaprepitant
- fosinopril
- fosphenytoin
- fostamatinib
- fruquintinib
G
- ganciclovir
- gefitinib
- gemcitabine
- gemfibrozil
- gemtuzumab
- gilteritinib
- givosiran
- glofitamab
- gold sodium thiomalate
- goldenseal
- golimumab
- grepafloxacin
- griseofulvin
H
- haemophilus b conjugate (hboc) vaccine
- haemophilus b conjugate (prp-omp) vaccine
- haemophilus b conjugate (prp-t) vaccine
- hepatitis a adult vaccine
- hepatitis a pediatric vaccine
- hepatitis b adult vaccine
- hepatitis b pediatric vaccine
- histoplasmin
- human papillomavirus vaccine
- hydralazine
- hydroxychloroquine
- hydroxyurea
I
- ibritumomab
- ibuprofen
- idarubicin
- idecabtagene vicleucel
- idelalisib
- ifosfamide
- imatinib
- indinavir
- indomethacin
- infliximab
- influenza virus vaccine, h1n1, inactivated
- influenza virus vaccine, h1n1, live
- influenza virus vaccine, h5n1
- influenza virus vaccine, inactivated
- influenza virus vaccine, live
- inotersen
- inotuzumab ozogamicin
- interferon alfa-2a
- interferon alfa-2b
- interferon alfa-n1
- interferon alfacon-1
- interferon beta-1a
- interferon beta-1b
- interferon gamma-1b
- iodoquinol
- ipilimumab
- iptacopan
- isatuximab
- isavuconazonium
- isoniazid
- isotretinoin
- itraconazole
- ivacaftor
- ivosidenib
- ixabepilone
- ixazomib
J
K
L
- labetalol
- lactobacillus acidophilus
- lactobacillus reuteri
- lactobacillus rhamnosus
- lactobacillus rhamnosus gg
- lamivudine
- lapatinib
- larotrectinib
- lazertinib
- lefamulin
- leflunomide
- lenacapavir
- lenalidomide
- lenvatinib
- letermovir
- levodopa
- levofloxacin
- levoketoconazole
- linezolid
- lisinopril
- lisocabtagene maraleucel
- lomitapide
- lomustine
- lonafarnib
- lonapegsomatropin
- loncastuximab tesirine
- lorlatinib
- lovastatin
- lurbinectedin
- lutetium lu 177 dotatate
- lyme disease vaccine
M
- macitentan
- maralixibat
- maraviroc
- mavacamten
- mavorixafor
- measles virus vaccine
- mechlorethamine
- meclofenamate
- mefenamic acid
- meloxicam
- melphalan
- melphalan flufenamide
- meningococcal conjugate vaccine
- meningococcal group acwy conjugate-group b vaccine (cvx 316)
- meningococcal group acwy conjugate-group b vaccine (cvx 328)
- meningococcal group B vaccine
- meningococcal polysaccharide vaccine
- mephenytoin
- mephobarbital
- mercaptopurine
- metaxalone
- methimazole
- methotrexate
- methyldopa
- methyltestosterone
- metreleptin
- metronidazole
- mibefradil
- miconazole
- mifepristone
- milnacipran
- minocycline
- mipomersen
- mirikizumab
- mirvetuximab soravtansine
- mitapivat
- mitomycin
- mitotane
- mitoxantrone
- mixed respiratory vaccine
- mobocertinib
- modafinil
- moexipril
- momelotinib
- monomethyl fumarate
- mosunetuzumab
- moxifloxacin
- mumps skin test antigen
- mumps virus vaccine
N
- nabumetone
- nadofaragene firadenovec
- nafcillin
- naltrexone
- nandrolone
- naproxen
- natalizumab
- naxitamab
- nefazodone
- nelarabine
- nelfinavir
- nevirapine
- niacin
- niacinamide
- nicotinamide
- nifedipine
- nilotinib
- nilutamide
- nintedanib
- niraparib
- nirogacestat
- nitrofurantoin
- nivolumab
O
- ocrelizumab
- olaparib
- olutasidenib
- omacetaxine
- omaveloxolone
- onasemnogene abeparvovec
- oritavancin
- orlistat
- oxaliplatin
- oxandrolone
- oxaprozin
- oxcarbazepine
- oxymetholone
- ozanimod
P
- paclitaxel
- paclitaxel protein-bound
- pacritinib
- palbociclib
- palifermin
- panobinostat
- pasireotide
- pazopanib
- pegaspargase
- pegfilgrastim
- peginterferon alfa-2a
- peginterferon alfa-2b
- peginterferon beta-1a
- pembrolizumab
- pemetrexed
- pemoline
- pennyroyal
- penpulimab
- pentobarbital
- pentostatin
- perindopril
- pertussis, acellular
- pexidartinib
- phenazopyridine
- phenobarbital
- phenylbutazone
- phenytoin
- pioglitazone
- pirfenidone
- piroxicam
- pirtobrutinib
- pitavastatin
- plague vaccine
- pneumococcal 13-valent vaccine
- pneumococcal 15-valent conjugate vaccine
- pneumococcal 20-valent conjugate vaccine
- pneumococcal 21-valent conjugate vaccine
- pneumococcal 23-polyvalent vaccine
- pneumococcal 7-valent vaccine
- polatuzumab vedotin
- poliovirus vaccine, inactivated
- poliovirus vaccine, live, trivalent
- pomalidomide
- ponatinib
- ponesimod
- posaconazole
- pralatrexate
- pralsetinib
- pravastatin
- primidone
- propylthiouracil
- pyrazinamide
Q
R
- rabies vaccine, human diploid cell
- rabies vaccine, purified chick embryo cell
- radium 223 dichloride
- ramipril
- ranolazine
- red yeast rice
- regorafenib
- remdesivir
- repotrectinib
- resmetirom
- retifanlimab
- ribociclib
- rifabutin
- rifampin
- rifapentine
- rilonacept
- rilpivirine
- riluzole
- ritlecitinib
- ritonavir
- rofecoxib
- roflumilast
- ropeginterferon alfa-2b
- rosiglitazone
- rosuvastatin
- rotavirus vaccine
- rsv vaccine pref3, recombinant
- rsv vaccine, mrna
- rsv vaccine, pref a-pref b, recombinant
- rubella virus vaccine
- rucaparib
- rufinamide
- ruxolitinib
S
- saccharomyces boulardii lyo
- samarium sm 153 lexidronam
- saquinavir
- sargramostim
- sarilumab
- sars-cov-2 (covid-19) ad26 vaccine, recombinant
- sars-cov-2 (covid-19) chadox1 vaccine, recombinant
- sars-cov-2 (covid-19) mrna-lnp vaccine (cvx 308)
- sars-cov-2 (covid-19) mrna-lnp vaccine (cvx 309)
- sars-cov-2 (covid-19) mrna-lnp vaccine (cvx 310)
- sars-cov-2 (covid-19) nvx-cov2373 vaccine, recombinant
- sars-cov-2 (covid-19) nvx-cov2705 vaccine, adjuvanted
- sars-cov-2 (covid-19) rs-nanoparticle vaccine, recombinant
- sars-cov-2 mrna (tozinameran 5y-11y) vaccine
- sars-cov-2 mrna (tozinameran 6m-4y) vaccine
- sars-cov-2 mrna (tozinameran-tris-sucrose) vaccine
- sars-cov-2 mrna (tozinameran) vaccine
- sars-cov-2 mrna-1273 (6m-5y) vaccine
- sars-cov-2 mrna-1273 (6y-11y) vaccine
- sars-cov-2 mrna-1273 (booster only) vaccine
- sars-cov-2 nvx-cov2373 vaccine, recomb (cvx 313)
- sars-cov-2 pres dtm (booster only) vaccine, recombinant
- satralizumab
- secnidazole
- secobarbital
- selinexor
- selpercatinib
- simvastatin
- siponimod
- sipuleucel-T
- skin test antigens, multiple
- smallpox and mpox vaccine
- smallpox vaccine
- sodium phosphate p32
- somapacitan-beco
- somatrem
- somatrogon
- somatropin
- sorafenib
- sotorasib
- sparsentan
- st. john's wort
- stanozolol
- staphage lysate (spl)
- stavudine
- stiripentol
- streptococcus salivarius
- streptozocin
- strontium-89 chloride
- sulfadiazine
- sulfadoxine
- sulfamethizole
- sulfamethoxazole
- sulfasalazine
- sulfinpyrazone
- sulfisoxazole
- sulindac
- sunitinib
- suvorexant
- suzetrigine
T
- tacrine
- tacrolimus topical
- tafasitamab
- tagraxofusp
- taletrectinib
- talimogene laherparepvec
- talquetamab
- tamoxifen
- tarlatamab
- tazemetostat
- tbo-filgrastim
- teclistamab
- tecovirimat
- telaprevir
- telbivudine
- telisotuzumab vedotin
- telithromycin
- telotristat
- temozolomide
- teniposide
- tenofovir alafenamide
- tenofovir disoproxil
- tepotinib
- terbinafine
- teriflunomide
- testosterone
- testosterone topical
- tetanus toxoid
- thalidomide
- thioguanine
- thiotepa
- ticagrelor
- tick-borne encephalitis (inactivated) pediatric vaccine
- tick-borne encephalitis (inactivated) vaccine
- tinidazole
- tipranavir
- tisagenlecleucel
- tislelizumab
- tisotumab vedotin
- tizanidine
- tocilizumab
- tofacitinib
- tolcapone
- tolmetin
- tolvaptan
- topotecan
- toripalimab
- tovorafenib
- trandolapril
- tremelimumab
- treosulfan
- tretinoin
- trichophyton skin test
- trimetrexate
- trofinetide
- troglitazone
- troleandomycin
- trovafloxacin
- tuberculin purified protein derivative
- tucatinib
- typhoid vaccine, inactivated
- typhoid vaccine, live
U
V
- vadadustat
- valdecoxib
- valganciclovir
- valoctocogene roxaparvovec
- valproic acid
- varicella virus vaccine
- vemurafenib
- verapamil
- viloxazine
- vimseltinib
- vinblastine
- vincristine
- vincristine liposome
- vinorelbine
- vitamin e
- voclosporin
- vonoprazan
- vorasidenib
- voriconazole
- voxelotor
Y
Z
- zafirlukast
- zalcitabine
- zidovudine
- zileuton
- zolbetuximab
- zoster vaccine live
- zoster vaccine, recombinant
Yondelis alcohol/food interactions
There is 1 alcohol/food interaction with Yondelis (trabectedin).
Yondelis disease interactions
There are 5 disease interactions with Yondelis (trabectedin) which include:
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More about Yondelis (trabectedin)
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- During pregnancy
- FDA approval history
- Drug class: alkylating agents
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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