Rifampin Drug Interactions
Currently displaying a list of 766 drugs known to interact with rifampin.
- 296 major drug interactions
- 409 moderate drug interactions
- 61 minor drug interactions
Medications known to interact with rifampin
Note: Showing generic names only.
A
- abacavir
- abemaciclib
- abiraterone
- abrocitinib
- acalabrutinib
- acarbose
- acetaminophen
- acetohexamide
- acitretin
- acoramidis
- adagrasib
- ado-trastuzumab emtansine
- afatinib
- aldesleukin
- alectinib
- alfentanil
- aliskiren
- allopurinol
- alpelisib
- alprazolam
- aluminum carbonate
- aluminum hydroxide
- ambrisentan
- aminophylline
- aminosalicylic acid
- amiodarone
- amitriptyline
- amlodipine
- amobarbital
- amoxapine
- amprenavir
- anagrelide
- anisindione
- apixaban
- apremilast
- aprepitant
- aprocitentan
- aripiprazole
- armodafinil
- artesunate
- asciminib
- ashwaganda
- asparaginase erwinia chrysanthemi
- asparaginase escherichia coli
- atazanavir
- atezolizumab
- atogepant
- atomoxetine
- atorvastatin
- atovaquone
- atrasentan
- avacopan
- avanafil
- avapritinib
- avatrombopag
- avelumab
- axitinib
- azithromycin
B
- bcg
- bcg vaccine
- bedaquiline
- belinostat
- belumosudil
- belzutifan
- bempedoic acid
- benazepril
- bendamustine
- bepridil
- berotralstat
- betamethasone
- betrixaban
- bexagliflozin
- bexarotene
- bicalutamide
- binimetinib
- bisoprolol
- black cohosh
- blinatumomab
- boceprevir
- bortezomib
- bosentan
- bosutinib
- brentuximab
- brexpiprazole
- brigatinib
- brincidofovir
- brivaracetam
- bromfenac
- bromocriptine
- budesonide
- buprenorphine
- bupropion
- buspirone
- butabarbital
- butalbital
- butorphanol
C
- cabazitaxel
- cabotegravir
- cabozantinib
- calaspargase pegol
- calcifediol
- calcitriol
- calcium carbonate
- canagliflozin
- cannabidiol
- capivasertib
- capmatinib
- captopril
- carbamazepine
- carfilzomib
- cariprazine
- carmustine
- carvedilol
- caspofungin
- cefamandole
- cefazolin
- cefmetazole
- cefoperazone
- cefotetan
- ceftobiprole medocaril
- celecoxib
- cemiplimab
- ceritinib
- cerivastatin
- cevimeline
- chaparral
- chenodiol
- chloramphenicol
- chlordiazepoxide
- chloroquine
- chlorotrianisene
- chlorpropamide
- chlorzoxazone
- cholecalciferol
- cholera vaccine, live
- cilostazol
- citalopram
- cladribine
- clarithromycin
- clavulanate
- clindamycin
- clobazam
- clofarabine
- clofibrate
- clomipramine
- clonazepam
- clopidogrel
- clorazepate
- clotrimazole
- clozapine
- cobicistat
- cobimetinib
- codeine
- comfrey
- conjugated estrogens
- conjugated estrogens topical
- copanlisib
- cortisone
- cosibelimab
- crinecerfont
- crizotinib
- cyclosporine
- cytarabine
D
- dabigatran
- dabrafenib
- dacarbazine
- daclatasvir
- daclizumab
- danazol
- danicopan
- dantrolene
- dapagliflozin
- daprodustat
- dapsone
- dapsone topical
- daridorexant
- darifenacin
- darolutamide
- darunavir
- dasatinib
- deferasirox
- deflazacort
- dehydroepiandrosterone
- delandistrogene moxeparvovec
- delavirdine
- demeclocycline
- desipramine
- deucravacitinib
- deuruxolitinib
- dexamethasone
- dexlansoprazole
- diazepam
- diclofenac
- diclofenac topical
- dicumarol
- didanosine
- dienestrol topical
- diethylstilbestrol
- digitoxin
- digoxin
- dihydroergotamine
- dihydrotachysterol
- diltiazem
- dimethyl fumarate
- diroximel fumarate
- disopyramide
- disulfiram
- divalproex sodium
- docetaxel
- dofetilide
- dolasetron
- dolutegravir
- donepezil
- doravirine
- dostarlimab
- doxepin
- doxepin topical
- doxercalciferol
- doxorubicin
- doxorubicin liposomal
- doxycycline
- dronedarone
- droperidol
- drospirenone
- duloxetine
- durvalumab
- duvelisib
E
- edoxaban
- efavirenz
- eflornithine
- elacestrant
- elafibranor
- elagolix
- eliglustat
- eltrombopag
- eluxadoline
- elvitegravir
- empagliflozin
- emtricitabine
- enalapril
- enalaprilat
- enasidenib
- encorafenib
- enfortumab vedotin
- enfuvirtide
- ensartinib
- entrectinib
- enzalutamide
- epirubicin
- eplerenone
- eravacycline
- erdafitinib
- ergocalciferol
- ergonovine
- ergotamine
- erlotinib
- erythromycin
- escitalopram
- esomeprazole
- estazolam
- esterified estrogens
- estradiol
- estradiol topical
- estrone
- estropipate
- estropipate topical
- eszopiclone
- ethambutol
- ethanol
- ethinyl estradiol
- ethionamide
- ethotoin
- etodolac
- etonogestrel
- etranacogene dezaparvovec
- etrasimod
- etravirine
- etretinate
- everolimus
- exemestane
- ezetimibe
F
- febuxostat
- fecal microbiota spores, live
- fecal microbiota, live
- fedratinib
- felbamate
- felodipine
- fenfluramine
- fenofibrate
- fenofibric acid
- fenoprofen
- fentanyl
- fesoterodine
- fexinidazole
- fexofenadine
- fezolinetant
- fidanacogene elaparvovec
- finerenone
- fitusiran
- flibanserin
- fluconazole
- fludrocortisone
- fluoxymesterone
- flurazepam
- flurbiprofen
- flutamide
- fluvastatin
- fosamprenavir
- fosaprepitant
- fosinopril
- fosphenytoin
- fostamatinib
- fostemsavir
- fruquintinib
- futibatinib
G
- gadoxetate disodium
- ganaxolone
- gefitinib
- gemcitabine
- gemfibrozil
- gemtuzumab
- gepirone
- gilteritinib
- glasdegib
- glimepiride
- glipizide
- glyburide
- grepafloxacin
- guanfacine
H
- halazepam
- haloperidol
- halothane
- hemin
- hydrocodone
- hydrocortisone
- hydroxychloroquine
- hydroxyprogesterone
I
- ibrexafungerp
- ibrutinib
- ibuprofen
- idelalisib
- imatinib
- imipramine
- indinavir
- indium oxyquinoline in-111
- indomethacin
- infigratinib
- infliximab
- inotuzumab ozogamicin
- interferon alfa-2a
- interferon alfa-2b
- interferon alfa-n1
- interferon alfacon-1
- interferon beta-1a
- interferon beta-1b
- interferon gamma-1b
- ipilimumab
- iptacopan
- irinotecan
- irinotecan liposomal
- isavuconazonium
- isoniazid
- isotretinoin
- isradipine
- istradefylline
- itraconazole
- ivabradine
- ivacaftor
- ivosidenib
- ixabepilone
- ixazomib
K
L
- labetalol
- lacosamide
- lamivudine
- lamotrigine
- lansoprazole
- lanthanum carbonate
- lapatinib
- larotrectinib
- lazertinib
- lefamulin
- leflunomide
- lemborexant
- lenacapavir
- lenalidomide
- leniolisib
- lenvatinib
- lesinurad
- letermovir
- levamlodipine
- levobupivacaine
- levofloxacin
- levoketoconazole
- levomethadyl acetate
- levonorgestrel
- levothyroxine
- levothyroxine / liothyronine
- lidocaine
- linagliptin
- linezolid
- liothyronine
- liotrix
- lisinopril
- lomitapide
- lomustine
- lonafarnib
- lorlatinib
- losartan
- lovastatin
- lumateperone
- lurasidone
- lurbinectedin
M
- macimorelin
- macitentan
- magaldrate
- magnesium carbonate
- magnesium hydroxide
- maralixibat
- maraviroc
- maribavir
- mavacamten
- mavorixafor
- meclofenamate
- medroxyprogesterone
- mefenamic acid
- mefloquine
- megestrol
- melatonin
- meloxicam
- mephenytoin
- mephobarbital
- mercaptopurine
- metaxalone
- metformin
- methadone
- methimazole
- methohexital
- methotrexate
- methoxyflurane
- methyldopa
- methylergonovine
- methylprednisolone
- methyltestosterone
- methysergide maleate
- metoprolol
- metronidazole
- mexiletine
- mibefradil
- midazolam
- midostaurin
- mifepristone
- milnacipran
- minocycline
- mipomersen
- mirabegron
- mirikizumab
- mirtazapine
- mitapivat
- mitotane
- mobocertinib
- modafinil
- moexipril
- momelotinib
- monomethyl fumarate
- montelukast
- morphine
- moxifloxacin
- mycophenolate mofetil
- mycophenolic acid
N
- nabumetone
- naldemedine
- naloxegol
- naltrexone
- nandrolone
- naproxen
- natalizumab
- nefazodone
- nelfinavir
- neratinib
- nevirapine
- niacin
- niacinamide
- nicardipine
- nicotinamide
- nifedipine
- nilotinib
- nilutamide
- nimodipine
- nintedanib
- nirogacestat
- nisoldipine
- nitisinone
- nitrofurantoin
- nivolumab
- norethindrone
- norgestrel
- nortriptyline
O
- obeticholic acid
- olanzapine
- olaparib
- oliceridine
- olutasidenib
- omaveloxolone
- omeprazole
- onasemnogene abeparvovec
- ondansetron
- orlistat
- osilodrostat
- osimertinib
- ospemifene
- oxaliplatin
- oxandrolone
- oxaprozin
- oxcarbazepine
- oxtriphylline
- oxycodone
- oxymetholone
- oxytetracycline
- ozanimod
P
- paclitaxel
- paclitaxel protein-bound
- pacritinib
- palbociclib
- paliperidone
- palovarotene
- panobinostat
- pantoprazole
- paricalcitol
- pasireotide
- pazopanib
- pegaspargase
- peginterferon alfa-2a
- peginterferon alfa-2b
- peginterferon beta-1a
- pembrolizumab
- pemigatinib
- pemoline
- penbutolol
- pennyroyal
- penpulimab
- pentobarbital
- perampanel
- perindopril
- pexidartinib
- phenazopyridine
- phenobarbital
- phenylbutazone
- phenytoin
- pimavanserin
- pioglitazone
- pirfenidone
- piroxicam
- pirtobrutinib
- pitavastatin
- pitolisant
- polatuzumab vedotin
- pomalidomide
- ponatinib
- ponesimod
- posaconazole
- pralatrexate
- pralsetinib
- pravastatin
- praziquantel
- prednisolone
- prednisone
- pretomanid
- primidone
- probenecid
- progesterone
- progesterone topical
- propafenone
- propofol
- propranolol
- propylthiouracil
- protriptyline
- pyrazinamide
Q
R
- rabeprazole
- raltegravir
- ramelteon
- ramipril
- ranolazine
- red yeast rice
- regorafenib
- relugolix
- remdesivir
- repaglinide
- repotrectinib
- resmetirom
- retifanlimab
- revefenacin
- revumenib
- ribociclib
- rilpivirine
- riluzole
- rimegepant
- riociguat
- ripretinib
- risperidone
- ritlecitinib
- ritonavir
- rivaroxaban
- rofecoxib
- roflumilast
- rolapitant
- romidepsin
- ropeginterferon alfa-2b
- ropivacaine
- rosiglitazone
- rosuvastatin
- rucaparib
- ruxolitinib
- ruxolitinib topical
S
- sacituzumab govitecan
- saquinavir
- satralizumab
- saxagliptin
- secobarbital
- seladelpar
- selexipag
- selinexor
- selpercatinib
- selumetinib
- sertraline
- sildenafil
- silodosin
- simeprevir
- simvastatin
- siponimod
- sirolimus
- sirolimus protein-bound
- sodium bicarbonate
- sofosbuvir
- solifenacin
- sonidegib
- sorafenib
- sotagliflozin
- sotorasib
- sparsentan
- stanozolol
- stavudine
- stiripentol
- sufentanil
- sulfadiazine
- sulfadoxine
- sulfamethizole
- sulfamethoxazole
- sulfasalazine
- sulfisoxazole
- sulindac
- sunitinib
- suvorexant
- suzetrigine
T
- tacrine
- tacrolimus
- tadalafil
- tamoxifen
- tarlatamab
- tasimelteon
- tazemetostat
- teclistamab
- telaprevir
- telisotuzumab vedotin
- telithromycin
- temozolomide
- temsirolimus
- tenofovir alafenamide
- tenofovir disoproxil
- tepotinib
- terbinafine
- teriflunomide
- testosterone
- testosterone topical
- tetracycline
- theophylline
- thioguanine
- thiopental
- thiotepa
- thyroid desiccated
- ticagrelor
- timolol
- tinidazole
- tipranavir
- tislelizumab
- tisotumab vedotin
- tivozanib
- tizanidine
- tocainide
- tocilizumab
- tofacitinib
- tolazamide
- tolbutamide
- tolcapone
- tolmetin
- tolvaptan
- toremifene
- toripalimab
- tovorafenib
- trabectedin
- tramadol
- trandolapril
- trazodone
- tremelimumab
- treprostinil
- tretinoin
- triamcinolone
- triazolam
- trimethoprim
- trimetrexate
- trimipramine
- trofinetide
- troglitazone
- troleandomycin
- trovafloxacin
- tucatinib
- typhoid vaccine, live
U
V
- vadadustat
- valbenazine
- valdecoxib
- valoctocogene roxaparvovec
- valproic acid
- valsartan
- vamorolone
- vandetanib
- vemurafenib
- venetoclax
- verapamil
- vilazodone
- vimseltinib
- vinblastine
- vincristine
- vincristine liposome
- vinorelbine
- voclosporin
- vonoprazan
- vorapaxar
- vorasidenib
- voriconazole
- vortioxetine
- voxelotor
W
Z
- zafirlukast
- zalcitabine
- zaleplon
- zanubrutinib
- zavegepant
- zidovudine
- zileuton
- ziprasidone
- zolpidem
- zonisamide
- zuranolone
Rifampin alcohol/food interactions
There is 1 alcohol/food interaction with rifampin.
Rifampin disease interactions
There are 6 disease interactions with rifampin which include:
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More about rifampin
- rifampin consumer information
- Check interactions
- Compare alternatives
- Pricing & coupons
- Reviews (22)
- Drug images
- Side effects
- Dosage information
- During pregnancy
- Drug class: rifamycin derivatives
- Breastfeeding
- En español
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
