Drug interactions between praziquantel and rifampin
Interactions between your drugs
Applies to: rifampin and praziquantel
Using praziquantel together with rifAMPin is not recommended. Combining these medications may significantly decrease the blood levels of praziquantel and make it ineffective or less effective in treating your condition. Your doctor may be able to prescribe an alternative to praziquantel that you can take with rifAMPin, or you may need to discontinue rifAMPin for up to four weeks before you begin taking praziquantel. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Drug and food interactions
Applies to: praziquantel
Food can enhance the levels of praziquantel in your body. To ensure maximal oral absorption, praziquantel should be administered with or immediately after a meal. This will make it easier for your body to absorb the medication. If you are receiving therapy with praziquantel you should avoid grapefruits and grapefruit juice. Grapefruit can raise the levels of praziquantel in your body and increase side effects of dizziness, abdominal discomfort, and nausea.. Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor.
Therapeutic duplication warnings
No therapeutic duplications were found for your selected drugs.
Drug Interaction Classification
|Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.|
|Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.|
|Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.|
|No information available.|
Do not stop taking any medications without consulting your healthcare provider.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.