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Drug interactions between praziquantel and rifampin

Results for the following 2 drugs:
praziquantel
rifampin

Interactions between your drugs

Major

rifAMPin praziquantel

Applies to: rifampin and praziquantel

Using praziquantel together with rifAMPin is not recommended. Combining these medications may significantly decrease the blood levels of praziquantel and make it ineffective or less effective in treating your condition. Your doctor may be able to prescribe an alternative to praziquantel that you can take with rifAMPin, or you may need to discontinue rifAMPin for up to four weeks before you begin taking praziquantel. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

Moderate

praziquantel food

Applies to: praziquantel

Food can enhance the levels of praziquantel in your body. To ensure maximal oral absorption, praziquantel should be administered with or immediately after a meal. This will make it easier for your body to absorb the medication. If you are receiving therapy with praziquantel you should avoid grapefruits and grapefruit juice. Grapefruit can raise the levels of praziquantel in your body and increase side effects of dizziness, abdominal discomfort, and nausea.. Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor.

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Therapeutic duplication warnings

No therapeutic duplications were found for your selected drugs.

Drug Interaction Classification

The classifications below are a guideline only. The relevance of a particular drug interaction to a specific patient is difficult to determine using this tool alone given the large number of variables that may apply.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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