Protriptyline Interactions
There are 694 drugs known to interact with protriptyline, along with 20 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 143 are major, 526 are moderate, and 25 are minor.
- View all 694 medications that may interact with protriptyline
- View protriptyline alcohol/food interactions (1)
- View protriptyline disease interactions (20)
Most frequently checked interactions
View interaction reports for protriptyline and the medicines listed below.
- Abilify (aripiprazole)
- Adderall (amphetamine / dextroamphetamine)
- Adderall XR (amphetamine / dextroamphetamine)
- Ambien (zolpidem)
- Benadryl (diphenhydramine)
- CoQ10 (ubiquinone)
- Crestor (rosuvastatin)
- Cymbalta (duloxetine)
- Emgality (galcanezumab)
- Fish Oil (omega-3 polyunsaturated fatty acids)
- Klonopin (clonazepam)
- Lamictal (lamotrigine)
- Latuda (lurasidone)
- Linzess (linaclotide)
- Lyrica (pregabalin)
- Metoprolol Tartrate (metoprolol)
- MiraLAX (polyethylene glycol 3350)
- Nexium (esomeprazole)
- Nuvigil (armodafinil)
- Singulair (montelukast)
- Synthroid (levothyroxine)
- Trintellix (vortioxetine)
- Ubrelvy (ubrogepant)
- Vitamin B12 (cyanocobalamin)
- Vitamin C (ascorbic acid)
- Vitamin D3 (cholecalciferol)
- Vraylar (cariprazine)
- Vyvanse (lisdexamfetamine)
- Xanax (alprazolam)
- Zyrtec (cetirizine)
Protriptyline alcohol/food interactions
There is 1 alcohol/food interaction with protriptyline.
Protriptyline disease interactions
There are 20 disease interactions with protriptyline which include:
- anticholinergic effects
- cardiovascular disease
- pheochromocytoma
- acute myocardial infarction recovery
- cardiovascular disease
- seizure disorders
- bone marrow suppression
- diabetes
- renal/liver disease
- schizophrenia/bipolar disorder
- tardive dyskinesia
- acute alcohol intoxication
- bipolar disorder screening
- glaucoma
- hyper/hypoglycemia
- liver/renal disease
- neutropenia
- schizophrenia
- thyroid disorders
- urinary retention
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More about protriptyline
- protriptyline consumer information
- Compare alternatives
- Pricing & coupons
- Reviews (4)
- Drug images
- Side effects
- Dosage information
- During pregnancy
- Drug class: tricyclic antidepressants
- Breastfeeding
- En español
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
