Ibrance Drug Interactions
Currently displaying a list of 487 drugs known to interact with Ibrance (palbociclib).
- 97 major drug interactions
- 366 moderate drug interactions
- 24 minor drug interactions
Medications known to interact with Ibrance
Note: Showing generic names only.
A
- abametapir topical
- abemaciclib
- abrocitinib
- acalabrutinib
- adagrasib
- adalimumab
- adenovirus vaccine
- alefacept
- alemtuzumab
- alfentanil
- allogeneic processed thymus tissue
- alpelisib
- aminoglutethimide
- amiodarone
- amobarbital
- amprenavir
- anakinra
- anthrax vaccine adsorbed
- apalutamide
- apixaban
- aprepitant
- aripiprazole
- armodafinil
- asciminib
- astemizole
- atazanavir
- atezolizumab
- atogepant
- atorvastatin
- avacopan
- avapritinib
- avelumab
- axitinib
- azathioprine
B
- baricitinib
- bcg
- bcg vaccine
- belzutifan
- berotralstat
- bexarotene
- bifidobacterium infantis
- bifidobacterium longum
- binimetinib
- boceprevir
- bosentan
- bosutinib
- brewer's yeast
- brigatinib
- bromocriptine
- budesonide
- budesonide nasal
- buprenorphine
- butabarbital
- butalbital
C
- cabazitaxel
- canakinumab
- candida albicans extract
- capivasertib
- carbamazepine
- cariprazine
- cemiplimab
- cenobamate
- ceritinib
- cerivastatin
- certolizumab
- cevimeline
- chikungunya vaccine, live (cvx 317)
- chikungunya vaccine, recombinant (cvx 329)
- chloramphenicol
- chloramphenicol ophthalmic
- chloramphenicol otic
- cholera vaccine
- cholera vaccine, live
- cilostazol
- cimetidine
- ciprofloxacin
- cisapride
- citalopram
- cladribine
- clarithromycin
- clotrimazole
- clozapine
- cobicistat
- cobimetinib
- coccidioidin skin test
- colchicine
- conivaptan
- copanlisib
- cosibelimab
- COVID-19 mRNA (Moderna) vaccine
- COVID-19 mRNA (Pfizer) vaccine
- crizotinib
- cyclosporine
D
- dabrafenib
- danazol
- daridorexant
- darifenacin
- darolutamide
- darunavir
- dasatinib
- deferasirox
- deferiprone
- delavirdine
- dengue vaccine
- denosumab
- deucravacitinib
- dexamethasone
- dihydroergotamine
- diltiazem
- dimethyl fumarate
- diroximel fumarate
- docetaxel
- dofetilide
- donepezil
- doravirine
- dostarlimab
- dronedarone
- drospirenone
- durvalumab
- dutasteride
- duvelisib
E
- echinacea
- efalizumab
- efavirenz
- efbemalenograstim alfa
- eflapegrastim
- elacestrant
- elafibranor
- elagolix
- eletriptan
- eliglustat
- encorafenib
- enfortumab vedotin
- entrectinib
- enzalutamide
- ergonovine
- ergotamine
- erythromycin
- escitalopram
- eslicarbazepine
- etanercept
- etrasimod
- etravirine
- everolimus
F
- fedratinib
- felbamate
- fenfluramine
- fentanyl
- fesoterodine
- fexinidazole
- filgrastim
- finerenone
- fingolimod
- flibanserin
- fluconazole
- fluvoxamine
- fosamprenavir
- fosaprepitant
- fosphenytoin
- fostamatinib
- futibatinib
G
- ganaxolone
- ganciclovir
- gefitinib
- gepirone
- gilteritinib
- givinostat
- glasdegib
- goldenseal
- golimumab
- grepafloxacin
- griseofulvin
- guanfacine
H
- haemophilus b conjugate (hboc) vaccine
- haemophilus b conjugate (prp-omp) vaccine
- haemophilus b conjugate (prp-t) vaccine
- halofantrine
- hepatitis a adult vaccine
- hepatitis a pediatric vaccine
- hepatitis b adult vaccine
- hepatitis b pediatric vaccine
- histoplasmin
- human papillomavirus vaccine
I
- ibrutinib
- idelalisib
- imatinib
- indacaterol
- indinavir
- infigratinib
- infliximab
- influenza virus vaccine, h1n1, inactivated
- influenza virus vaccine, h1n1, live
- influenza virus vaccine, h5n1
- influenza virus vaccine, inactivated
- influenza virus vaccine, live
- ipilimumab
- iptacopan
- irinotecan
- irinotecan liposomal
- isavuconazonium
- isoniazid
- itraconazole
- ivabradine
- ivacaftor
- ivosidenib
J
K
L
- lactobacillus acidophilus
- lactobacillus reuteri
- lactobacillus rhamnosus
- lactobacillus rhamnosus gg
- lanreotide
- lapatinib
- larotrectinib
- lazertinib
- lefamulin
- leflunomide
- lemborexant
- lenacapavir
- letermovir
- levobupivacaine
- levoketoconazole
- levomethadyl acetate
- lomitapide
- lonafarnib
- lonapegsomatropin
- loncastuximab tesirine
- lorlatinib
- lovastatin
- lumateperone
- lurasidone
- lurbinectedin
- lusutrombopag
- lyme disease vaccine
M
- macitentan
- maraviroc
- mavacamten
- mavorixafor
- measles virus vaccine
- meningococcal conjugate vaccine
- meningococcal group acwy conjugate-group b vaccine (cvx 316)
- meningococcal group B vaccine
- meningococcal polysaccharide vaccine
- mephobarbital
- methadone
- methylergonovine
- methysergide maleate
- metreleptin
- mibefradil
- miconazole
- midazolam
- midostaurin
- mifepristone
- mirabegron
- mirtazapine
- mitapivat
- mitotane
- mixed respiratory vaccine
- mobocertinib
- modafinil
- monomethyl fumarate
- morphine
- mumps skin test antigen
- mumps virus vaccine
N
- nadofaragene firadenovec
- nafcillin
- naloxegol
- natalizumab
- nefazodone
- nelfinavir
- nevirapine
- nifedipine
- nilotinib
- nintedanib
- niraparib
- nirogacestat
- nitisinone
- nivolumab
O
- ocrelizumab
- octreotide
- olaparib
- oliceridine
- olutasidenib
- omacetaxine
- omaveloxolone
- oritavancin
- osilodrostat
- osimertinib
- oxcarbazepine
- oxycodone
- ozanimod
P
- paclitaxel
- paclitaxel protein-bound
- pacritinib
- palovarotene
- panobinostat
- pasireotide
- pazopanib
- pegfilgrastim
- pembrolizumab
- pemigatinib
- pentobarbital
- pertussis, acellular
- pexidartinib
- phenobarbital
- phenylbutazone
- phenytoin
- pimavanserin
- pimecrolimus topical
- pimozide
- pirtobrutinib
- plague vaccine
- pneumococcal 13-valent vaccine
- pneumococcal 15-valent conjugate vaccine
- pneumococcal 20-valent conjugate vaccine
- pneumococcal 21-valent conjugate vaccine
- pneumococcal 23-polyvalent vaccine
- pneumococcal 7-valent vaccine
- polatuzumab vedotin
- poliovirus vaccine, inactivated
- poliovirus vaccine, live, trivalent
- ponesimod
- posaconazole
- pralsetinib
- primidone
- prucalopride
Q
R
- rabies vaccine, human diploid cell
- rabies vaccine, purified chick embryo cell
- radium 223 dichloride
- ranolazine
- red yeast rice
- remdesivir
- repotrectinib
- retapamulin topical
- retifanlimab
- revumenib
- ribociclib
- rifabutin
- rifampin
- rifapentine
- rilonacept
- rilpivirine
- rimegepant
- ripretinib
- ritlecitinib
- ritonavir
- roflumilast
- roflumilast topical
- ropeginterferon alfa-2b
- ropivacaine
- rotavirus vaccine
- rsv vaccine pref3, recombinant
- rsv vaccine, mrna
- rsv vaccine, pref a-pref b, recombinant
- rubella virus vaccine
- rucaparib
- rufinamide
- ruxolitinib
- ruxolitinib topical
S
- saccharomyces boulardii lyo
- samarium sm 153 lexidronam
- saquinavir
- sargramostim
- sars-cov-2 (covid-19) ad26 vaccine, recombinant
- sars-cov-2 (covid-19) chadox1 vaccine, recombinant
- sars-cov-2 (covid-19) mrna-lnp vaccine (cvx 308)
- sars-cov-2 (covid-19) mrna-lnp vaccine (cvx 309)
- sars-cov-2 (covid-19) mrna-lnp vaccine (cvx 310)
- sars-cov-2 (covid-19) nvx-cov2373 vaccine, recombinant
- sars-cov-2 (covid-19) rs-nanoparticle vaccine, recombinant
- sars-cov-2 mrna (tozinameran 5y-11y) vaccine
- sars-cov-2 mrna (tozinameran 6m-4y) vaccine
- sars-cov-2 mrna (tozinameran-tris-sucrose) vaccine
- sars-cov-2 mrna (tozinameran) vaccine
- sars-cov-2 mrna-1273 (6m-5y) vaccine
- sars-cov-2 mrna-1273 (6y-11y) vaccine
- sars-cov-2 mrna-1273 (booster only) vaccine
- sars-cov-2 nvx-cov2373 vaccine, recomb (cvx 313)
- sars-cov-2 pres dtm (booster only) vaccine, recombinant
- saxagliptin
- secobarbital
- seladelpar
- selpercatinib
- selumetinib
- sibutramine
- sildenafil
- silodosin
- simvastatin
- siponimod
- sipuleucel-T
- sirolimus
- sirolimus protein-bound
- skin test antigens, multiple
- smallpox and mpox vaccine
- smallpox vaccine
- sodium phosphate p32
- solifenacin
- somapacitan-beco
- somatrem
- somatrogon
- somatropin
- sonidegib
- sotorasib
- sparsentan
- st. john's wort
- staphage lysate (spl)
- stiripentol
- streptococcus salivarius
- strontium-89 chloride
- sufentanil
- sulfinpyrazone
- suvorexant
- suzetrigine
T
- tacrolimus
- tadalafil
- talazoparib
- talimogene laherparepvec
- tazemetostat
- tbo-filgrastim
- tecovirimat
- telaprevir
- telithromycin
- telotristat
- temsirolimus
- tepotinib
- terfenadine
- teriflunomide
- tetanus toxoid
- thiotepa
- ticagrelor
- tick-borne encephalitis (inactivated) pediatric vaccine
- tick-borne encephalitis (inactivated) vaccine
- tislelizumab
- tofacitinib
- tolterodine
- topotecan
- toremifene
- toripalimab
- tovorafenib
- trabectedin
- tramadol
- tremelimumab
- treosulfan
- triazolam
- trichophyton skin test
- trofinetide
- troglitazone
- troleandomycin
- tuberculin purified protein derivative
- tucatinib
- typhoid vaccine, inactivated
- typhoid vaccine, live
U
V
- vadadustat
- valganciclovir
- vardenafil
- varicella virus vaccine
- vemurafenib
- venetoclax
- venlafaxine
- verapamil
- vibegron
- viloxazine
- vinblastine
- vincristine
- vincristine liposome
- vinorelbine
- vonoprazan
- vorasidenib
- voriconazole
- voxelotor
Y
Z
- zafirlukast
- zanubrutinib
- ziprasidone
- zolpidem
- zonisamide
- zoster vaccine live
- zoster vaccine, recombinant
Ibrance alcohol/food interactions
There is 1 alcohol/food interaction with Ibrance (palbociclib).
Ibrance disease interactions
There are 5 disease interactions with Ibrance (palbociclib) which include:
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More about Ibrance (palbociclib)
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- Drug class: CDK 4/6 inhibitors
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Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
