Linaclotide Interactions
There are 59 drugs known to interact with linaclotide, along with 2 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 10 are moderate, and 49 are minor.
- View all 59 medications that may interact with linaclotide
- View linaclotide alcohol/food interactions (1)
- View linaclotide disease interactions (2)
Most frequently checked interactions
View interaction reports for linaclotide and the medicines listed below.
- Advair Diskus (fluticasone / salmeterol)
- Aspir 81 (aspirin)
- Aspirin Low Strength (aspirin)
- Benadryl (diphenhydramine)
- Concerta (methylphenidate)
- Cymbalta (duloxetine)
- Dexilant (dexlansoprazole)
- Flonase (fluticasone nasal)
- L-Carnitine (levocarnitine)
- Lithium Carbonate ER (lithium)
- Lyrica (pregabalin)
- Metoprolol Succinate ER (metoprolol)
- MiraLAX (polyethylene glycol 3350)
- Myrbetriq (mirabegron)
- Ozempic (semaglutide)
- Paracetamol (acetaminophen)
- Restasis (cyclosporine ophthalmic)
- Symbicort (budesonide / formoterol)
- Synthroid (levothyroxine)
- Tramadol Hydrochloride ER (tramadol)
- Trintellix (vortioxetine)
- Tylenol (acetaminophen)
- Vitamin B12 (cyanocobalamin)
- Vitamin C (ascorbic acid)
- Vitamin D3 (cholecalciferol)
- Vyvanse (lisdexamfetamine)
- Wellbutrin XL (bupropion)
- Xanax (alprazolam)
- Zinc (zinc sulfate)
- Zyrtec (cetirizine)
Linaclotide alcohol/food interactions
There is 1 alcohol/food interaction with linaclotide.
Linaclotide disease interactions
There are 2 disease interactions with linaclotide which include:
Report options
More about linaclotide
- linaclotide consumer information
- Compare alternatives
- Reviews (929)
- Side effects
- Dosage information
- During pregnancy
- Drug class: guanylate cyclase-C agonists
- Breastfeeding
- En español
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
See also:
MiraLAX
MiraLAX (polyethylene glycol) is used as a laxative to treat occasional constipation or irregular ...
Colace
Colace makes bowel movements softer and is used to treat or prevent constipation. Includes Colace ...
Ozempic
Learn about Ozempic (semaglutide) for type 2 diabetes treatment, weight management, cardiovascular ...
Linzess
Linzess (linaclotide) is used to treat chronic idiopathic constipation, irritable bowel syndrome ...
Bentyl
Bentyl is used to treat functional bowel or irritable bowel syndrome. Bentyl may also be used for ...
Xifaxan
Xifaxan (rifaximin) is used to treat travelers' diarrhea, irritable bowel syndrome with diarrhea ...
Dulcolax
Dulcolax (bisacodyl) is a laxative used to treat constipation. Includes Dulcolax side effects ...
Hyoscyamine
Hyoscyamine systemic is used for anesthesia, anticholinesterase poisoning, crohn's disease ...
Magnesium oxide
Magnesium oxide systemic is used for constipation, duodenal ulcer, GERD, hypomagnesemia ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
