Linaclotide Interactions
There are 59 drugs known to interact with linaclotide, along with 2 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 10 are moderate, and 49 are minor.
- View all 59 medications that may interact with linaclotide
- View linaclotide alcohol/food interactions (1)
- View linaclotide disease interactions (2)
Most frequently checked interactions
View interaction reports for linaclotide and the medicines listed below.
- Advair Diskus (fluticasone / salmeterol)
- Aspir 81 (aspirin)
- Aspirin Low Strength (aspirin)
- Benadryl (diphenhydramine)
- Concerta (methylphenidate)
- Crestor (rosuvastatin)
- Cymbalta (duloxetine)
- Dexilant (dexlansoprazole)
- Flonase (fluticasone nasal)
- L-Carnitine (levocarnitine)
- Lasix (furosemide)
- Lithium Carbonate ER (lithium)
- Lyrica (pregabalin)
- Metoprolol Succinate ER (metoprolol)
- MiraLAX (polyethylene glycol 3350)
- Myrbetriq (mirabegron)
- Ozempic (semaglutide)
- Paracetamol (acetaminophen)
- Restasis (cyclosporine ophthalmic)
- Symbicort (budesonide / formoterol)
- Synthroid (levothyroxine)
- Tramadol Hydrochloride ER (tramadol)
- Trintellix (vortioxetine)
- Tylenol (acetaminophen)
- Vitamin B12 (cyanocobalamin)
- Vitamin C (ascorbic acid)
- Vitamin D3 (cholecalciferol)
- Wellbutrin XL (bupropion)
- Xanax (alprazolam)
- Zyrtec (cetirizine)
Linaclotide alcohol/food interactions
There is 1 alcohol/food interaction with linaclotide.
Linaclotide disease interactions
There are 2 disease interactions with linaclotide which include:
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More about linaclotide
- linaclotide consumer information
- Compare alternatives
- Reviews (929)
- Side effects
- Dosage information
- During pregnancy
- Drug class: guanylate cyclase-C agonists
- Breastfeeding
- En español
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
