Makena Drug Interactions
Currently displaying a list of 232 drugs known to interact with Makena (hydroxyprogesterone).
- 18 major drug interactions
- 206 moderate drug interactions
- 8 minor drug interactions
Medications known to interact with Makena
Note: Showing generic names only.
- abametapir topical
- abrocitinib
- acarbose
- acetaminophen
- acetohexamide
- adagrasib
- albiglutide
- alogliptin
- alosetron
- aminoglutethimide
- amobarbital
- anagrelide
- apalutamide
- aprepitant
- armodafinil
- asciminib
- asenapine
- atorvastatin
- avacopan
- baricitinib
- belzutifan
- bendamustine
- berotralstat
- bexagliflozin
- bexarotene
- binimetinib
- boceprevir
- bosentan
- brigatinib
- bupropion
- butabarbital
- butalbital
- caffeine
- canagliflozin
- carbamazepine
- cenobamate
- chloramphenicol
- chlorpropamide
- cholestyramine
- clarithromycin
- clotrimazole
- clozapine
- colestipol
- conivaptan
- cyclobenzaprine
- cyclosporine
- dabrafenib
- dapagliflozin
- daridorexant
- darunavir
- dasatinib
- deferasirox
- dexamethasone
- diltiazem
- divalproex sodium
- dronedarone
- dulaglutide
- duloxetine
- duvelisib
- echinacea
- efavirenz
- elafibranor
- elagolix
- empagliflozin
- encorafenib
- enzalutamide
- ertugliflozin
- erythromycin
- eslicarbazepine
- etravirine
- exenatide
- fedratinib
- felbamate
- fenfluramine
- fexinidazole
- fluconazole
- flutamide
- fluvoxamine
- fosaprepitant
- fosphenytoin
- fostamatinib
- frovatriptan
- indinavir
- insulin
- insulin aspart
- insulin aspart protamine
- insulin degludec
- insulin detemir
- insulin glargine
- insulin glulisine
- insulin inhalation, rapid acting
- insulin isophane
- insulin lispro
- insulin lispro protamine
- insulin regular
- insulin zinc
- insulin zinc extended
- iptacopan
- isavuconazonium
- itraconazole
- ivacaftor
- ivosidenib
- lamotrigine
- lapatinib
- larotrectinib
- lefamulin
- lenacapavir
- letermovir
- letrozole
- levobupivacaine
- levoketoconazole
- lidocaine
- linagliptin
- liraglutide
- lixisenatide
- lonafarnib
- lonapegsomatropin
- lorlatinib
- mavacamten
- melatonin
- mephobarbital
- metformin
- methadone
- mibefradil
- miconazole
- miglitol
- mitapivat
- mitotane
- mobocertinib
- modafinil
- momelotinib
- pacritinib
- pentobarbital
- pexidartinib
- phenobarbital
- phenylbutazone
- phenytoin
- pioglitazone
- pirfenidone
- pirtobrutinib
- pitolisant
- posaconazole
- pralsetinib
- pramlintide
- primidone
- propofol
- ramelteon
- rasagiline
- repaglinide
- repotrectinib
- ribociclib
- rifabutin
- rifampin
- rifapentine
- riluzole
- ritlecitinib
- ropinirole
- ropivacaine
- rosiglitazone
- rucaparib
- rufinamide
- ruxolitinib
- ruxolitinib topical
- saquinavir
- saxagliptin
- secobarbital
- selegiline
- selpercatinib
- semaglutide
- sirolimus
- sitagliptin
- somapacitan-beco
- somatrem
- somatrogon
- somatropin
- sotagliflozin
- sotorasib
- st. john's wort
- stiripentol
- sulfinpyrazone
- suzetrigine
- tacrine
- tacrolimus
- tasimelteon
- tazemetostat
- tecovirimat
- telaprevir
- telithromycin
- telotristat
- temsirolimus
- theophylline
- thiabendazole
- thiotepa
- tirzepatide
- tizanidine
- tofacitinib
- tolazamide
- tolbutamide
- tovorafenib
- trofinetide
- troglitazone
- troleandomycin
Makena alcohol/food interactions
There are 6 alcohol/food interactions with Makena (hydroxyprogesterone).
Makena disease interactions
There are 10 disease interactions with Makena (hydroxyprogesterone) which include:
- breast malignancy
- liver disease
- thromboembolism
- depression
- fluid retention
- glucose intolerance
- retinal thrombosis
- thyroid function tests
- hyperlipidemia
- weight gain
Report options
More about Makena (hydroxyprogesterone)
- Makena consumer information
- Check interactions
- Compare alternatives
- Reviews (153)
- Side effects
- Dosage information
- During pregnancy
- FDA approval history
- Drug class: progestins
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.